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- Title
Hepatitis E Virus Seroprevalence Among Blood Donors in Bushehr, South of Iran.
- Authors
Naeimi, Behrouz; Kalimani, Farnaz Mazloom; Pourfatolah, Ali Akbar; Azimzadeh, Masoud; Mankhian, Alireza; Akbarzadeh, Samad; Hajiani, Gholamreza; Kooshesh, Faramarz; Khamisipour, Gholamreza
- Abstract
Background: Although so far several studies have determined the hepatitis E virus (HEV) prevalence in some parts of Iran, no data exists regarding the HEV seroprevalence in Bushehr province as the southernmost point in Iran yet. Objectives: The aim of this study was to evaluate the seroprevalence of anti-HEV IgG among the blood donors in Bushehr. Patients and Methods: A total of 628 blood donor samples were collected from September to October 2013, after obtaining informed written consents, and analyzed for the presence of anti-HEV IgG using commercial HEV enzyme-linked immunosorbent assay (ELISA) kit. All the samples were tested by two ELISA kits and evaluated for liver function test. Results: Overall, 105 (16.7%) blood samples were positive for HEV-specific-IgG antibodies, while 523 (83.8%) were negative. The presence of anti-HEV IgG was not associated with gender; however, it was correlated with age. It was indicated that the anti-HEV prevalence increases by age and there was a significant difference between the age groups regarding HEV seropositivity. Conclusions: High HEV seroprevalence (16.7%) was observed among the blood donors in Bushehr province. It appears that exposure to HEV increases with age; although, more people should be examined.
- Subjects
IRAN; BLOOD donors; CHI-squared test; ENZYME-linked immunosorbent assay; HEPATITIS E; RESEARCH; RESEARCH funding; T-test (Statistics); SEROPREVALENCE; DATA analysis software
- Publication
Hepatitis Monthly, 2015, Vol 15, Issue 11, p1
- ISSN
1735-143X
- Publication type
Article
- DOI
10.5812/hepatmon.29219