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OREXIN 1 AND 2 RECEPTOR INVOLVEMENT IN CO2 -INDUCED PANIC-ASSOCIATED BEHAVIOR AND AUTONOMIC RESPONSES.
- Published in:
- 2015
- By:
- Publication type:
- journal article
OREXIN 1 AND 2 RECEPTOR INVOLVEMENT IN CO<sub>2</sub>-INDUCED PANIC-ASSOCIATED BEHAVIOR AND AUTONOMIC RESPONSES.
- Published in:
- Depression & Anxiety (1091-4269), 2015, v. 32, n. 9, p. 671, doi. 10.1002/da.22403
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- Publication type:
- Article
High Throughput Monitoring of Amyloid-β<sub>42</sub> Assembly into Soluble Oligomers Achieved by Sensitive Conformation State-Dependent Immunoassays.
- Published in:
- Journal of Alzheimer's Disease, 2011, v. 25, n. 4, p. 655, doi. 10.3233/JAD-2011-102022
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- Publication type:
- Article
INTERVENTION OF TAU PATHOLOGY PREVENTS BEHAVIORAL CHANGES IN RTG4510 MOUSE MODEL OF TAUOPATHY.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P845, doi. 10.1016/j.jalz.2016.06.1731
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- Publication type:
- Article
EARLY CLINICAL RESULTS AND PRECLINICAL VALIDATION OF THE O-GLCNACASE (OGA) INHIBITOR MK-8719 AS A NOVEL THERAPEUTIC FOR THE TREATMENT OF TAUOPATHIES.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P261, doi. 10.1016/j.jalz.2016.06.469
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- Publication type:
- Article
A CELLULAR EXPRESSION MODEL OF TAU HYPERPHOSPHORYLATION AND AGGREGATION THAT DOES NOT UTILIZE FRONTOTEMPORAL DEMENTIA MUTATIONS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P842, doi. 10.1016/j.jalz.2016.06.1724
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- Publication type:
- Article
Models of tau pathology in induced pluripotent stem cell-derived human neurons.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P621, doi. 10.1016/j.jalz.2015.06.872
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- Publication type:
- Article
A novel multivalent Abeta peptide vaccine with preclinical evidence of a central immune response that generates antisera recognizing a wide range of Abeta peptide species
- Published in:
- 2010
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- Publication type:
- Abstract
P4-332: In vivo pharmacodynamic effects of BQCA, a novel selective allosteric M1 receptor modulator
- Published in:
- 2008
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- Publication type:
- Abstract
Orexin 2 Receptor Antagonism is Sufficient to Promote NREM and REM Sleep from Mouse to Man.
- Published in:
- Scientific Reports, 2016, p. 27147, doi. 10.1038/srep27147
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- Publication type:
- Article
Intracellular Clusterin Interacts with Brain Isoforms of the Bridging Integrator 1 and with the Microtubule-Associated Protein Tau in Alzheimer's Disease.
- Published in:
- PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0103187
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- Publication type:
- Article
Uncovering the Genetic Landscape for Multiple Sleep- Wake Traits.
- Published in:
- PLoS ONE, 2009, v. 4, n. 4, p. 1, doi. 10.1371/journal.pone.0005161
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- Publication type:
- Article
Orexin receptor antagonist-induced sleep does not impair the ability to wake in response to emotionally salient acoustic stimuli in dogs.
- Published in:
- Frontiers in Behavioral Neuroscience, 2014, v. 8, p. 1, doi. 10.3389/fnbeh.2014.00182
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- Publication type:
- Article
Selective T-Type Calcium Channel Block in Thalamic Neurons Reveals Channel Redundancy and Physiological Impact of I<sub>Twindow</sub>.
- Published in:
- Journal of Neuroscience, 2010, v. 30, n. 1, p. 99, doi. 10.1523/JNEUROSCI.4305-09.2010
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- Publication type:
- Article
PET imaging of M4 muscarinic acetylcholine receptors in rhesus macaques using [ 11 C]MK-6884: Quantification with kinetic modeling and receptor occupancy by CVL-231 (emraclidine), a novel positive allosteric modulator.
- Published in:
- Journal of Cerebral Blood Flow & Metabolism, 2024, v. 44, n. 8, p. 1329, doi. 10.1177/0271678X241238820
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- Publication type:
- Article
Differential sleep-promoting effects of dual orexin receptor antagonists and GABA<sub>A</sub> receptor modulators.
- Published in:
- BMC Neuroscience, 2014, v. 15, n. 1, p. 109, doi. 10.1186/1471-2202-15-109
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- Publication type:
- Article
Differential sleep-promoting effects of dual orexin receptor antagonists and GABAA receptor modulators.
- Published in:
- 2014
- By:
- Publication type:
- journal article
The duration of sleep promoting efficacy by dual orexin receptor antagonists is dependent upon receptor occupancy threshold.
- Published in:
- BMC Neuroscience, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2202-14-90
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- Publication type:
- Article
The duration of sleep promoting efficacy by dual orexin receptor antagonists is dependent upon receptor occupancy threshold.
- Published in:
- 2013
- By:
- Publication type:
- journal article
Quantitative Electroencephalography Within Sleep/Wake States Differentiates GABA<sub>A</sub> Modulators Eszopiclone and Zolpidem From Dual Orexin Receptor Antagonists in Rats.
- Published in:
- Neuropsychopharmacology, 2013, v. 38, n. 12, p. 2401, doi. 10.1038/npp.2013.139
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- Publication type:
- Article
Dual orexin receptor antagonists show distinct effects on locomotor performance, ethanol interaction and sleep architecture relative to gamma-aminobutyric acid-A receptor modulators.
- Published in:
- Frontiers in Neuroscience, 2013, v. 7, p. 1, doi. 10.3389/fnins.2013.00254
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- Publication type:
- Article
Parkinson disease among patients treated for benign prostatic hyperplasia with α1 adrenergic receptor antagonists.
- Published in:
- 2021
- By:
- Publication type:
- journal article
The dual orexin receptor antagonist, DORA-22, lowers histamine levels in the lateral hypothalamus and prefrontal cortex without lowering hippocampal acetylcholine.
- Published in:
- Journal of Neurochemistry, 2017, v. 142, n. 2, p. 204, doi. 10.1111/jnc.14055
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- Publication type:
- Article
Early-stage comparative effectiveness: Randomized controlled trial with histamine inverse agonist MK-7288 in excessive daytime sleepiness patients.
- Published in:
- Journal of Clinical Pharmacology, 2013, v. 53, n. 12, p. 1294, doi. 10.1002/jcph.182
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- Publication type:
- Article
Control of firing patterns through modulation of axon initial segment T-type calcium channels.
- Published in:
- Journal of Physiology, 2012, v. 590, n. 1, p. 109, doi. 10.1113/jphysiol.2011.218768
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- Publication type:
- Article
Presynaptic HCN1 channels regulate Ca<sub>V</sub>3.2 activity and neurotransmission at select cortical synapses.
- Published in:
- Nature Neuroscience, 2011, v. 14, n. 4, p. 478, doi. 10.1038/nn.2757
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- Publication type:
- Article
Knocking the NT4 gene into the BDNF locus rescues BDNF deficient mice and reveals distinct NT4 and BDNF activities.
- Published in:
- Nature Neuroscience, 2000, v. 3, n. 4, p. 350, doi. 10.1038/73921
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- Publication type:
- Article
Systemic treatment with liver X receptor agonists raises apolipoprotein E, cholesterol, and amyloid-β peptides in the cerebral spinal fluid of rats.
- Published in:
- Molecular Neurodegeneration, 2010, v. 5, p. 44, doi. 10.1186/1750-1326-5-44
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- Publication type:
- Article
Discovery of a Pharmacologically Active Antagonist of the Two-Pore-Domain Potassium Channel K<sub>2P</sub>9.1 (TASK-3).
- Published in:
- ChemMedChem, 2012, v. 7, n. 1, p. 123, doi. 10.1002/cmdc.201100351
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- Publication type:
- Article
A Comparative Study on the Lysosomal Cation Channel TMEM175 Using Automated Whole-Cell Patch-Clamp, Lysosomal Patch-Clamp, and Solid Supported Membrane-Based Electrophysiology: Functional Characterization and High-Throughput Screening Assay Development.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 16, p. 12788, doi. 10.3390/ijms241612788
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- Publication type:
- Article
Internalized Tau Oligomers Cause Neurodegeneration by Inducing Accumulation of Pathogenic Tau in Human Neurons Derived from Induced Pluripotent Stem Cells.
- Published in:
- Journal of Neuroscience, 2015, v. 35, n. 42, p. 14234, doi. 10.1523/JNEUROSCI.1523-15.2015
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- Publication type:
- Article
A Sensitive Aβ Oligomer Assay Discriminates Alzheimer's and Aged Control Cerebrospinal Fluid.
- Published in:
- Journal of Neuroscience, 2014, v. 34, n. 8, p. 2884, doi. 10.1523/JNEUROSCI.1675-13.2014
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- Publication type:
- Article
Essential Thalamic Contribution to Slow Waves of Natural Sleep.
- Published in:
- Journal of Neuroscience, 2013, v. 33, n. 50, p. 19599, doi. 10.1523/JNEUROSCI.3169-13.2013
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- Publication type:
- Article
Calcineurin Signaling Mediates Activity-Dependent Relocation of the Axon Initial Segment.
- Published in:
- Journal of Neuroscience, 2013, v. 33, n. 16, p. 6950, doi. 10.1523/JNEUROSCI.0277-13.2013
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- Publication type:
- Article
Biphasic Cholinergic Synaptic Transmission Controls Action Potential Activity in Thalamic Reticular Nucleus Neurons.
- Published in:
- Journal of Neuroscience, 2013, v. 33, n. 5, p. 2048, doi. 10.1523/JNEUROSCI.3177-12.2013
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- Publication type:
- Article
T-Type Calcium Channels Consolidate Tonic Action Potential Output of Thalamic Neurons to Neocortex.
- Published in:
- Journal of Neuroscience, 2012, v. 32, n. 35, p. 12228, doi. 10.1523/JNEUROSCI.1362-12.2012
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- Publication type:
- Article
Presynaptic Ca<sub>V</sub>3.2 Channels Regulate Excitatory Neurotransmission in Nociceptive Dorsal Horn Neurons.
- Published in:
- Journal of Neuroscience, 2012, v. 32, n. 27, p. 9374, doi. 10.1523/JNEUROSCI.0068-12.2012
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- Publication type:
- Article
GABAergic Synaptic Transmission Triggers Action Potentials in Thalamic Reticular Nucleus Neurons.
- Published in:
- Journal of Neuroscience, 2012, v. 32, n. 23, p. 7782, doi. 10.1523/JNEUROSCI.0839-12.2012
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- Publication type:
- Article
Nerve Terminal Nicotinic Acetylcholine Receptors Initiate Quantal GABA Release from Perisomatic Interneurons by Activating Axonal T-Type (Ca<sub>v</sub>3) Ca<sup>2+</sup> Channels and Ca<sup>2+</sup> Release from Stores.
- Published in:
- Journal of Neuroscience, 2011, v. 31, n. 38, p. 13546, doi. 10.1523/JNEUROSCI.2781-11.2011
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- Publication type:
- Article
State-Dependent Firing Determines Intrinsic Dendritic Ca<sup>2+</sup> Signaling in Thalamocortical Neurons.
- Published in:
- Journal of Neuroscience, 2010, v. 30, n. 44, p. 14843, doi. 10.1523/JNEUROSCI.2968-10.2010
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- Publication type:
- Article
Genetic Deletion and Pharmacological Inhibition of Phosphodiesterase 10A Protects Mice From Diet-Induced Obesity and Insulin Resistance.
- Published in:
- Diabetes, 2014, v. 63, n. 1, p. 300, doi. 10.2337/db13-0247
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- Publication type:
- Article