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Electrocardiogram Abnormalities Suggest Aberrant Cardiac Conduction in Huntington's Disease.
Published in:
Movement Disorders Clinical Practice, 2018, v. 5, n. 3, p. 306, doi. 10.1002/mdc3.12596
By:
- Stephen, Christopher D.;
- Hung, Judy;
- Schifitto, Giovanni;
- Hersch, Steven M.;
- Rosas, H. Diana
Publication type:
Article
The Vasopressin 1a Receptor Antagonist SRX246 Reduces Aggressive Behavior in Huntington's Disease.
Published in:
Journal of Personalized Medicine, 2022, v. 12, n. 10, p. 1561, doi. 10.3390/jpm12101561
By:
- Maibach, Hilda T.;
- Brownstein, Michael J.;
- Hersch, Steven M.;
- Anderson, Karen E.;
- Itzkowitz, Debra E.;
- Damiano, Eve M.;
- Simon, Neal G.
Publication type:
Article
Histone Deacetylase Inhibition by Sodium Butyrate Chemotherapy Ameliorates the Neurodegenerative Phenotype in Huntington's Disease Mice.
Published in:
Journal of Neuroscience, 2003, v. 23, n. 28, p. 9418, doi. 10.1523/JNEUROSCI.23-28-09418.2003
By:
- Ferrante, Robert J.;
- Kubilus, James K.;
- Junghee Lee;
- Hoon Ryu;
- Beesen, Ayshe;
- Zucker, Birgit;
- Smith, Karen;
- Kowall, Neil W.;
- Ratan, Rajiv R.;
- Luthi-Carter, Ruth;
- Hersch, Steven M.
Publication type:
Article
Safety and Tolerability of SRX246, a Vasopressin 1a Antagonist, in Irritable Huntington's Disease Patients—A Randomized Phase 2 Clinical Trial.
Published in:
Journal of Clinical Medicine, 2020, v. 9, n. 11, p. 3682, doi. 10.3390/jcm9113682
By:
- Brownstein, Michael J.;
- Simon, Neal G.;
- Long, Jeffrey D.;
- Yankey, Jon;
- Maibach, Hilda T.;
- Cudkowicz, Merit;
- Coffey, Christopher;
- Conwit, Robin A.;
- Lungu, Codrin;
- Anderson, Karen E.;
- Hersch, Steven M.;
- Ecklund, Dixie J.;
- Damiano, Eve M.;
- Itzkowitz, Debra E.;
- Lu, Shifang;
- Chase, Marianne K.;
- Shefner, Jeremy M.;
- McGarry, Andrew;
- Thornell, Brenda;
- Gladden, Catherine
Publication type:
Article
Complexity and Heterogeneity: What Drives the Ever-changing Brain in Huntington's Disease?
Published in:
Annals of the New York Academy of Sciences, 2008, v. 1147, p. 196, doi. 10.1196/annals.1427.034
By:
- Rosas, H. Diana;
- Salat, David H.;
- Lee, Stephanie Y.;
- Zaleta, Alexandra K.;
- Hevelone, Nathanael;
- Hersch, Steven M.
Publication type:
Article
Thalamocortical synapses of pyramidal cells which project from SmI to MsI cortex in the mouse.
Published in:
Journal of Comparative Neurology, 1981, v. 198, n. 1, p. 167, doi. 10.1002/cne.901980114
By:
- White, Edward L.;
- Hersch, Steven M.
Publication type:
Article
Thalamocortical synapses involving identified neurons in mouse primary somatosensory cortex: A terminal degeneration and golgi/EM study.
Published in:
Journal of Comparative Neurology, 1981, v. 195, n. 2, p. 253, doi. 10.1002/cne.901950206
By:
- Hersch, Steven M.;
- White, Edward L.
Publication type:
Article
Subcellular localization and molecular topology of the dopamine transporter in the striatum and substantia nigra.
Published in:
Journal of Comparative Neurology, 1997, v. 388, n. 2, p. 211, doi. 10.1002/(SICI)1096-9861(19971117)388:2<211::AID-CNE3>3.0.CO;2-4
By:
- Hersch, Steven M.;
- Yi, Hong;
- Heilman, Craig J.;
- Edwards, Robert H.;
- Levey, Allan I.
Publication type:
Article
Light and electron microscopic study of m2 muscarinic acetylcholine receptor in the basal forebrain of the rat.
Published in:
Journal of Comparative Neurology, 1995, v. 351, n. 3, p. 339, doi. 10.1002/cne.903510303
By:
- Levey, Allan I.;
- Edmunds, Sharon M.;
- Hersch, Steven M.;
- Wiley, Ronald G.;
- Heilman, Craig J.
Publication type:
Article
Cortical inputs to m2-immunoreactive striatal interneurons in rat and monkey.
Published in:
Synapse, 2000, v. 37, n. 4, p. 252, doi. 10.1002/1098-2396(20000915)37:4<252::AID-SYN2>3.0.CO;2-A
By:
- Thomas, Traci M.;
- Smith, Yol;
- Levey, Allan I.;
- Hersch, Steven M.
Publication type:
Article
Neuroprotective Effects of Synaptic Modulation in Huntington's Disease R6/2 Mice.
Published in:
Journal of Neuroscience, 2007, v. 27, n. 47, p. 12908, doi. 10.1523/JNEUROSCI.4318-07.2007
By:
- Stack, Edward C.;
- Dedeoglu, Alpaslan;
- Smith, Karen M.;
- Cormier, Kerry;
- Kubilus, James K.;
- Bogdanov, Mikhail;
- Matson, Wayne R.;
- Lichuan Yang;
- Jenkins, Bruce G.;
- Luthi-Carter, Ruth;
- Kowall, Neil W.;
- Hersch, Steven M.;
- Beal, M. Flint;
- Ferrante, Robert J.
Publication type:
Article
Cerebral cortex and the clinical expression of Huntington's disease: complexity and heterogeneity.
Published in:
2008
By:
- Rosas HD;
- Salat DH;
- Lee SY;
- Zaleta AK;
- Pappu V;
- Fischl B;
- Greve D;
- Hevelone N;
- Hersch SM;
- Rosas, H Diana;
- Salat, David H;
- Lee, Stephanie Y;
- Zaleta, Alexandra K;
- Pappu, Vasanth;
- Fischl, Bruce;
- Greve, Doug;
- Hevelone, Nathanael;
- Hersch, Steven M
Publication type:
journal article
Cerebral cortex and the clinical expression of Huntingtons disease: complexity and heterogeneity.
Published in:
Brain: A Journal of Neurology, 2008, v. 131, n. 4, p. 1057, doi. 10.1093/brain/awn025
By:
- H. Diana Rosas;
- David H. Salat;
- Stephanie Y. Lee;
- Alexandra K. Zaleta;
- Vasanth Pappu;
- Bruce Fischl;
- Doug Greve;
- Nathanael Hevelone;
- Steven M. Hersch
Publication type:
Article
Muscarinic m1 and m2 receptor proteins in local circuit and projection neurons of the primate striatum: Anatomical evidence for cholinergic modulation of glutamatergic prefronto-striatal pathways.
Published in:
Journal of Comparative Neurology, 2001, v. 434, n. 4, p. 445, doi. 10.1002/cne.1186
By:
- Alcantara, Adriana A.;
- Mrzljak, Ladislav;
- Jakab, Robert L.;
- Levey, Allan I.;
- Hersch, Steven M.;
- Goldman-Rakic, Patricia S.
Publication type:
Article
The Sirtuin 2 microtubule deacetylase is an abundant neuronal protein that accumulates in the aging CNS.
Published in:
Human Molecular Genetics, 2011, v. 20, n. 20, p. 3986, doi. 10.1093/hmg/ddr326
By:
- Maxwell, Michele M.;
- Tomkinson, Elizabeth M.;
- Nobles, Johnathan;
- Wizeman, John W.;
- Amore, Allison M.;
- Quinti, Luisa;
- Chopra, Vanita;
- Hersch, Steven M.;
- Kazantsev, Aleksey G.
Publication type:
Article
Thalamocortical and other synapses involving nonspiny multipolar cells of mouse SmI cortex.
Published in:
Journal of Comparative Neurology, 1984, v. 229, n. 3, p. 311, doi. 10.1002/cne.902290303
By:
- White, Edward L.;
- Benshalom, Gadi;
- Hersch, Steven M.
Publication type:
Article
A quantitative study of the thalamocortical and other synapses in layer IV of pyramidal cells projecting from mouse SmI cortex to the caudate-putamen nucleus.
Published in:
Journal of Comparative Neurology, 1982, v. 211, n. 3, p. 217, doi. 10.1002/cne.902110302
By:
- Hersch, Steven M.;
- White, Edward L.
Publication type:
Article
The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse model of Huntington's disease.
Published in:
Molecular Neurodegeneration, 2010, v. 5, p. 26, doi. 10.1186/1750-1326-5-26
By:
- Fox, Jonathan H.;
- Connor, Teal;
- Chopra, Vanita;
- Dorsey, Kate;
- Kama, Jibrin A.;
- Bleckmann, Dorothee;
- Betschart, Claudia;
- Hoyer, Daniel;
- Frentzel, Stefan;
- DiFiglia, Marian;
- Paganetti, Paolo;
- Hersch, Steven M.
Publication type:
Article
Histones associated with downregulated genes are hypo-acetylated in Huntington's disease models.
Published in:
Human Molecular Genetics, 2007, v. 16, n. 11, p. 1293, doi. 10.1093/hmg/ddm078
By:
- Sadri-Vakili, Ghazaleh;
- Bouzou, Bérengère;
- Benn, Caroline L.;
- Kim, Mee-Ohk;
- Chawla, Prianka;
- Overland, Ryan P.;
- Glajch, Kelly E.;
- Xia, Eva;
- Qiu, Zhihua;
- Hersch, Steven M.;
- Clark, Timothy W.;
- Yohrling, George J.;
- Cha, Jang-Ho J.
Publication type:
Article
HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis.
Published in:
Human Molecular Genetics, 2002, v. 11, n. 23, p. 2815, doi. 10.1093/hmg/11.23.2815
By:
- Singaraja, Roshni R.;
- Hadano, Shinji;
- Metzler, Martina;
- Givan, Scott;
- Wellington, Cheryl L.;
- Warby, Simon;
- Yanai, Anat;
- Gutekunst, Claire-Anne;
- Leavitt, Blair R.;
- Yi, Hong;
- Fichter, Keith;
- Gan, Lu;
- McCutcheon, Krista;
- Chopra, Vikramjit;
- Michel, Jennifer;
- Hersch, Steven M.;
- Ikeda, Joh-E;
- Hayden, Michael R.
Publication type:
Article
Impaired Cerebrovascular Reactivity in Huntington's Disease.
Published in:
Frontiers in Physiology, 2021, v. 12, p. 1, doi. 10.3389/fphys.2021.663898
By:
- Chan, Suk Tak;
- Mercaldo, Nathaniel D.;
- Kwong, Kenneth K.;
- Hersch, Steven M.;
- Rosas, Herminia D.
Publication type:
Article
Huntington aggregates may not predict neuronal death in Huntington's disease.
Published in:
1999
By:
- Kuemmerle, Stefan;
- Gutekunst, Claire-Anne;
- Klein, Autumn M.;
- Li, Xiao-Jiang;
- Li, Shi-Hua;
- Beal, M. Flint;
- Hersch, Steven M.;
- Ferrante, Robert J.;
- Kuemmerle, S;
- Gutekunst, C A;
- Klein, A M;
- Li, X J;
- Li, S H;
- Beal, M F;
- Hersch, S M;
- Ferrante, R J
Publication type:
journal article
Cystamine increasesl-cysteine levels in Huntington's disease transgenic mouse brain and in a PC12 model of polyglutamine aggregation.
Published in:
Journal of Neurochemistry, 2004, v. 91, n. 2, p. 413, doi. 10.1111/j.1471-4159.2004.02726.x
By:
- Fox, Jonathan H.;
- Barber, David S.;
- Singh, Bhupinder;
- Zucker, Birgit;
- Swindell, Mary K.;
- Norflus, Fran;
- Buzescu, Rodica;
- Chopra, Raman;
- Ferrante, Robert J.;
- Kazantsev, Aleksey;
- Hersch, Steven M.
Publication type:
Article
Creatine therapy provides neuroprotection after onset of clinical symptoms in Huntington's disease transgenic mice.
Published in:
Journal of Neurochemistry, 2003, v. 85, n. 6, p. 1359, doi. 10.1046/j.1471-4159.2003.01706.x
By:
- Dedeoglu, Alpaslan;
- Kubilus, James K.;
- Yang, Lichuan;
- Ferrante, Kimberly L.;
- Hersch, Steven M.;
- Beal, M. Flint;
- Ferrante, and Robert J.
Publication type:
Article
Association of HAP1 Isoforms with a Unique Cytoplasmic Structure.
Published in:
Journal of Neurochemistry, 1998, v. 71, n. 5, p. 2178, doi. 10.1046/j.1471-4159.1998.71052178.x
By:
- Li, Shi-Hua;
- Gutekunst, Claire-Anne;
- Hersch, Steven M.;
- Li, Xiao-Jiang
Publication type:
Article
A tale of two factors: What determines the rate of progression in Huntington's disease? A longitudinal MRI study.
Published in:
Movement Disorders, 2011, v. 26, n. 9, p. 1691, doi. 10.1002/mds.23762
By:
- Rosas, H. Diana;
- Reuter, Martin;
- Doros, Gheorghe;
- Lee, Stephanie Y.;
- Triggs, Tyler;
- Malarick, Keith;
- Fischl, Bruce;
- Salat, David H.;
- Hersch, Steven M.
Publication type:
Article
Diffusion tensor imaging in presymptomatic and early Huntington's disease: Selective white matter pathology and its relationship to clinical measures.
Published in:
Movement Disorders, 2006, v. 21, n. 9, p. 1317, doi. 10.1002/mds.20979
By:
- Rosas, H. Diana;
- Tuch, David S.;
- Hevelone, Nathanael D.;
- Zaleta, Alexandra K.;
- Vangel, Mark;
- Hersch, Steven M.;
- Salat, David H.
Publication type:
Article
A systems-level 'misunderstanding': the plasma metabolome in Huntington's disease.
Published in:
Annals of Clinical & Translational Neurology, 2015, v. 2, n. 7, p. 756, doi. 10.1002/acn3.214
By:
- Rosas, Herminia D.;
- Doros, Gheorghe;
- Bhasin, Swati;
- Thomas, Beena;
- Gevorkian, Sona;
- Malarick, Keith;
- Matson, Wayne;
- Hersch, Steven M.
Publication type:
Article

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