We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
THE DISTRIBUTION OF TYPE I (INSULIN-DEPENDENT) DIABETES MELLITUS BY AGE, SEX, SECULAR TREND, SEASONALITY, TIME CLUSTERS, AND SPACE-TIME CLUSTERS: EVIDENCE FROM MONTREAL, 1971–1983.
- Authors
SIEMIATYCKI, JACK; COLLE, ELEANOR; AUBERT, DENIS; CAMPBELL, SALLY; BELMONTE, MIMI M.
- Abstract
The etiology of insulin-dependent diabetes mellitus remains obscure. In an attempt to clarify some aspects of the epidemiology, including its compatibility with an acute infectious process, the authors undertook in-depth analyses of childhood cases accumulated in a population-based register in Montreal during the period from 1971-1983. Incidence rates increased with age until puberty, at which point they plateaued and decreased. There was no overall difference in incidence between males and females; however, the rate for females peaked approximately two years before the rate for males. While there was some variation overtime, there was no evidence of a long-term trend, nor was the yearly variation impressive in magnitude. The findings further indicate that the disease is not characterized by explosive outbreaks. There was slight seasonality, with a 28% higher rate of onset in fall and winter than in spring and summer. There was some evidence of space-time clustering in 1971–1973, but not thereafter. Taken as a whole, these findings do not support the hypothesis that a significant portion of insulin-dependent diabetes is caused by an acute infectious process.
- Publication
American Journal of Epidemiology, 1986, Vol 124, Issue 4, p545
- ISSN
0002-9262
- Publication type
Article
- DOI
10.1093/oxfordjournals.aje.a114427