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- Title
Acute Graft-Versus-Host Disease: A Brief Review.
- Authors
Aladağ, Elifcan; Kelkitli, Engin; Göker, Hakan
- Abstract
Graft-versus-host disease (GvHD) is an important complication that can be observed after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Acute GvHD (aGvHD) is seen after allo- HSCT and the incidence of aGvHD is around 30%-50%. aGvHD prophylaxis is essential in patients undergoing allo-HSCT. Initial therapy for aGvHD is steroids. Prognosis is poor in aGvHD patients not responding to steroids. In this article, the pathobiology, clinical findings, prophylaxis, and treatment of aGvHD will be summarized.
- Subjects
GRAFT versus host disease prevention; BONE marrow transplantation; GRAFT versus host disease; HEMATOPOIETIC stem cell transplantation; DISEASE risk factors
- Publication
Turkish Journal of Hematology, 2020, Vol 37, Issue 1, p1
- ISSN
1300-7777
- Publication type
Article
- DOI
10.4274/tjh.galenos.2019.2019.0157