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- Title
Synthesis and Insecticidal Activities of Chlorothiazolyl Analogs of Nitromethylene Neonicotinoids with Tetrahydropyridine Fixed cis-Configuration.
- Authors
Shao, Xusheng; Huang, Xinglong; Shi, Qian; Li, Zhong; Tao, Liming; Song, Gonghua
- Abstract
The chlorothiazolyl moiety was an effective bioisoster of chloropyridyl in pesticide molecular design. Replacement of chloropyridyl in cis-nitromethylene neonicotinoids with chlorothiazolyl generated the chlorothiazolyl counterpart of nitromethylene neonicotinoids with tetrahydropyridine fixed cis-configuration. Bioassay against cowpea aphis ( Aphis craccivora) indicated that the chlorothiazolyl analogs could maintain the high insecticidal activity.
- Subjects
ORGANIC synthesis; INSECTICIDES; THIAZOLES; NITROMETHYLENE compounds; NEONICOTINOIDS; PYRIDINE; BIOLOGICAL assay
- Publication
Journal of Heterocyclic Chemistry, 2012, Vol 49, Issue 5, p1136
- ISSN
0022-152X
- Publication type
Article
- DOI
10.1002/jhet.969