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- Title
The Genus Alnus, A Comprehensive Outline of Its Chemical Constituents and Biological Activities.
- Authors
Xueyang Ren; Ting He; Yanli Chang; Yicheng Zhao; Xiaoyi Chen; Shaojuan Bai; Le Wang; Meng Shen; Gaimei She
- Abstract
The genus Alnus (Betulaceae) is comprised of more than 40 species. Many species of this genus have a long history of use in folk medicines. Phytochemical investigations have revealed the presence of diarylheptanoids, polyphenols, flavonoids, terpenoids, steroids and other compounds. Diarylheptanoids, natural products with a 1,7-diphenylheptane structural skeleton, are the dominant constituents in the genus, whose anticancer effect has been brought into focus. Pure compounds and crude extracts from the genus exhibit a wide spectrum of pharmacological activities both in vitro and in vivo. This paper compiles 273 naturally occurring compounds from the genus Alnus along with their structures and pharmacological activities, as reported in 138 references.
- Subjects
ALDER; BIOACCUMULATION; ANTINEOPLASTIC agents; TRADITIONAL medicine; NATURAL products
- Publication
Molecules, 2017, Vol 22, Issue 8, p1383
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules22081383