We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
A Translational Model of Chronic Heart Failure.
- Authors
Kryzhanovskii, S. A.; Tsorin, I. B.; Stolyaruk, V. N.; Vititnova, M. B.; Ionova, E. O.; Barchukov, V. V.; Miroshkina, I. A.; Sorokina, A. V.; Kozhevnikova, L. M.; Durnev, A. D.
- Abstract
We created a translational model of chronic heart failure in rats that developed in 3 months after reproducing experimental anterior transmural myocardial infarction. The model simulated the basic clinicodiagnostic criteria of this disease: impaired contractility and dilatation of heart ventricles, signs of venous congestion, elevated plasma content of biochemical markers, and abnormal overexpression of AT1aR and β-adrenoceptors.
- Subjects
HEART failure; HEART dilatation; HEART ventricles; HYPEREMIA; BIOMARKERS
- Publication
Bulletin of Experimental Biology & Medicine, 2019, Vol 166, Issue 6, p706
- ISSN
0007-4888
- Publication type
Article
- DOI
10.1007/s10517-019-04604-y