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- Title
Pericarditis tuberculosa en paciente inmunocompetente. Reporte de caso.
- Authors
Felipe Reyes-Vega, Daniel; Buitrago-Toro, Kenny; Jiménez-Salazar, Silvana; Carlos-Álvarez, Luis
- Abstract
Tuberculous pericarditis is a rare extrapulmonary manifestation that affects less than 4% of patients with tuberculosis (TB). It has high morbidity and mortality at late diagnoses, especially in immunocompromised patients. Its presentation is unspecific. The symptomatology derives from the speed of installation of the pericardial effusion, with fatal cases being recorded due to cardiac tamponade. Diagnostic confirmation is obtained with the identification of mycobacteria in a pericardial sample fluid, with a high suspicion rate based on additional tests such as quantification of non-stimulated gamma interferon, pericardial lysozyme, and adenosine deaminase (ADA) in pericardial fluid. The treatment consists of a combination of anti-tuberculous therapy, pericardial drainage, and corticosteroids as an adjuvant. We present the case of a 64-year-old immunocompetent male, a frequent smoker in the past, with a high diagnostic suspicion for TB, confirmed positive for ADA (55,8 UI/L) in pericardial fluid. That allowed initiating an adequate treatment with subsequent clinical improvement during the follow-up.
- Subjects
ADENOSINE deaminase; INTERFERON gamma; PERICARDIAL effusion; TUBERCULOSIS patients; DIAGNOSIS; CARDIAC tamponade
- Publication
Duazary. Revista de la Facultad de Ciencias de la Salud, 2021, Vol 18, Issue 1, p99
- ISSN
1794-5992
- Publication type
Article
- DOI
10.21676/2389783X.3834