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High‐confidence calling of normal epithelial cells allows identification of a novel stem‐like cell state in the colorectal cancer microenvironment.
Published in:
International Journal of Cancer, 2024, v. 155, n. 9, p. 1655, doi. 10.1002/ijc.35079
By:
- Wei, Tzu‐Ting;
- Blanc, Eric;
- Peidli, Stefan;
- Bischoff, Philip;
- Trinks, Alexandra;
- Horst, David;
- Sers, Christine;
- Blüthgen, Nils;
- Beule, Dieter;
- Morkel, Markus;
- Obermayer, Benedikt
Publication type:
Article
Helicobacter pylori shows tropism to gastric differentiated pit cells dependent on urea chemotaxis.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33165-4
By:
- Aguilar, Carmen;
- Pauzuolis, Mindaugas;
- Pompaiah, Malvika;
- Vafadarnejad, Ehsan;
- Arampatzi, Panagiota;
- Fischer, Mara;
- Narres, Dominik;
- Neyazi, Mastura;
- Kayisoglu, Özge;
- Sell, Thomas;
- Blüthgen, Nils;
- Morkel, Markus;
- Wiegering, Armin;
- Germer, Christoph-Thomas;
- Kircher, Stefan;
- Rosenwald, Andreas;
- Saliba, Antoine-Emmanuel;
- Bartfeld, Sina
Publication type:
Article
Malignant transformation and genetic alterations are uncoupled in early colorectal cancer progression.
Published in:
BMC Biology, 2020, v. 18, n. 1, p. N.PAG, doi. 10.1186/s12915-020-00844-x
By:
- Mamlouk, Soulafa;
- Simon, Tincy;
- Tomás, Laura;
- Wedge, David C.;
- Arnold, Alexander;
- Menne, Andrea;
- Horst, David;
- Capper, David;
- Morkel, Markus;
- Posada, David;
- Sers, Christine;
- Bläker, Hendrik
Publication type:
Article
An inducible RNA interference system for the functional dissection of mouse embryogenesis.
Published in:
Nucleic Acids Research, 2010, v. 38, n. 11, p. e122, doi. 10.1093/nar/gkq199
By:
- Vidigal, Joana A.;
- Morkel, Markus;
- Wittler, Lars;
- Brouwer-Lehmitz, Antje;
- Grote, Phillip;
- Macura, Karol;
- Herrmann, Bernhard G.
Publication type:
Article
DNA methylation reveals distinct cells of origin for pancreatic neuroendocrine carcinomas and pancreatic neuroendocrine tumors.
Published in:
Genome Medicine, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13073-022-01018-w
By:
- Simon, Tincy;
- Riemer, Pamela;
- Jarosch, Armin;
- Detjen, Katharina;
- Di Domenico, Annunziata;
- Bormann, Felix;
- Menne, Andrea;
- Khouja, Slim;
- Monjé, Nanna;
- Childs, Liam H.;
- Lenze, Dido;
- Leser, Ulf;
- Rossner, Florian;
- Morkel, Markus;
- Blüthgen, Nils;
- Pavel, Marianne;
- Horst, David;
- Capper, David;
- Marinoni, Ilaria;
- Perren, Aurel
Publication type:
Article
An RNA Interference Phenotypic Screen Identifies a Role for FGF Signals in Colon Cancer Progression.
Published in:
PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0023381
By:
- Leushacke, Marc;
- Spörle, Ralf;
- Bernemann, Christof;
- Brouwer-Lehmitz, Antje;
- Fritzmann, Johannes;
- Theis, Mirko;
- Buchholz, Frank;
- Herrmann, Bernhard G.;
- Morkel, Markus
Publication type:
Article
Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10954-y
By:
- Brandt, Raphael;
- Sell, Thomas;
- Lüthen, Mareen;
- Uhlitz, Florian;
- Klinger, Bertram;
- Riemer, Pamela;
- Giesecke-Thiel, Claudia;
- Schulze, Silvia;
- El-Shimy, Ismail Amr;
- Kunkel, Desiree;
- Fauler, Beatrix;
- Mielke, Thorsten;
- Mages, Norbert;
- Herrmann, Bernhard G.;
- Sers, Christine;
- Blüthgen, Nils;
- Morkel, Markus
Publication type:
Article
Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-018-08140-7
By:
- Starossom, Sarah C.;
- Campo Garcia, Juliana;
- Woelfle, Tim;
- Romero-Suarez, Silvina;
- Olah, Marta;
- Watanabe, Fumihiro;
- Cao, Li;
- Yeste, Ada;
- Tukker, John J.;
- Quintana, Francisco J.;
- Imitola, Jaime;
- Witzel, Franziska;
- Schmitz, Dietmar;
- Morkel, Markus;
- Paul, Friedemann;
- Infante-Duarte, Carmen;
- Khoury, Samia J.
Publication type:
Article
The single‐cell transcriptional landscape of lung carcinoid tumors.
Published in:
International Journal of Cancer, 2022, v. 150, n. 12, p. 2058, doi. 10.1002/ijc.33995
By:
- Bischoff, Philip;
- Trinks, Alexandra;
- Wiederspahn, Jennifer;
- Obermayer, Benedikt;
- Pett, Jan Patrick;
- Jurmeister, Philipp;
- Elsner, Aron;
- Dziodzio, Tomasz;
- Rückert, Jens‐Carsten;
- Neudecker, Jens;
- Falk, Christine;
- Beule, Dieter;
- Sers, Christine;
- Morkel, Markus;
- Horst, David;
- Klauschen, Frederick;
- Blüthgen, Nils
Publication type:
Article
Identification of Y-Box Binding Protein 1 As a Core Regulator of MEK/ERK Pathway-Dependent Gene Signatures in Colorectal Cancer Cells.
Published in:
PLoS Pathogens, 2011, v. 7, n. 2, p. 1, doi. 10.1371/journal.pgen.1001231
By:
- Jürchott, Karsten;
- Kuban, Ralf-Jürgen;
- Krech, Till;
- Blüthgen, Nils;
- Stein, Ulrike;
- Walther, Wolfgang;
- Friese, Christian;
- Kielbasa, Szymon M.;
- Ungethüm, Ute;
- Lund, Per;
- Knösel, Thomas;
- Kemmner, Wolfgang;
- Morkel, Markus;
- Fritzmann, Johannes;
- Schlag, Peter M.;
- Birchmeier, Walter;
- Krueger, Tammo;
- Sperling, Silke;
- Sers, Christine;
- Royer, Hans-Dieter
Publication type:
Article
A Flexible Multiwell Format for Immunofluorescence Screening Microscopy of Small-Molecule Inhibitors.
Published in:
Assay & Drug Development Technologies, 2010, v. 8, n. 5, p. 571, doi. 10.1089/adt.2009.0260
By:
- Anne-Kathrin Scholz;
- Bert M. Klebl;
- Markus Morkel;
- Hans Lehrach;
- Andreas Dahl;
- Bodo M.H. Lange
Publication type:
Article
c-Met is essential for wound healing in the skin.
Published in:
Journal of Cell Biology, 2007, v. 177, n. 1, p. 151, doi. 10.1083/jcb.200701086
By:
- Chmielowiec, Jolanta;
- Borowiak, Malgorzata;
- Morkel, Markus;
- Stradal, Theresia;
- Munz, Barbara;
- Werner, Sabine;
- Wehland, Jürgen;
- Birchmeier, Carmen;
- Birchmeier, Walter
Publication type:
Article
Epigenetic regulation of Amphiregulin and Epiregulin in colorectal cancer.
Published in:
International Journal of Cancer, 2019, v. 144, n. 3, p. 569, doi. 10.1002/ijc.31892
By:
- Bormann, Felix;
- Stinzing, Sebastian;
- Tierling, Sascha;
- Morkel, Markus;
- Markelova, Maria Rivera;
- Walter, Jörn;
- Weichert, Wilko;
- Roßner, Florian;
- Kuhn, Natalia;
- Perner, Juliane;
- Dietz, Johanna;
- Ispasanie, Sylvia;
- Dietel, Manfred;
- Schäfer, Reinhold;
- Heinemann, Volker;
- Sers, Christine
Publication type:
Article
Wnt and BMP signals control intestinal adenoma cell fates.
Published in:
International Journal of Cancer, 2012, v. 131, n. 10, p. 2242, doi. 10.1002/ijc.27500
By:
- Farrall, Alexandra L.;
- Riemer, Pamela;
- Leushacke, Marc;
- Sreekumar, Amulya;
- Grimm, Christina;
- Herrmann, Bernhard G.;
- Morkel, Markus
Publication type:
Article
DNA--Methylome Analysis of Mouse Intestinal Adenoma Identifies a Tumour-Specific Signature That Is Partly Conserved in Human Colon Cancer.
Published in:
PLoS Genetics, 2013, v. 9, n. 2, p. 1, doi. 10.1371/journal.pgen.1003250
By:
- Grimm, Christina;
- Chavez, Lukas;
- Vilardell, Mireia;
- Farrall, Alexandra L.;
- Tierling, Sascha;
- Böhm, Julia W.;
- Grote, Phillip;
- Lienhard, Matthias;
- Dietrich, Jörn;
- Timmermann, Bernd;
- Walter, Jörn;
- Schweiger, Michal R.;
- Lehrach, Hans;
- Herwig, Ralf;
- Herrmann, Bernhard G.;
- Morkel, Markus
Publication type:
Article
Identification of Y-Box Binding Protein 1 As a Core Regulator of MEK/ERK Pathway-Dependent Gene Signatures in Colorectal Cancer Cells.
Published in:
PLoS Genetics, 2010, v. 6, n. 12, p. 1, doi. 10.1371/journal.pgen.1001231
By:
- Jürchott, Karsten;
- Kuban, Ralf-Jürgen;
- Krech, Till;
- Blüthgen, Nils;
- Stein, Ulrike;
- Walther, Wolfgang;
- Friese, Christian;
- Kielbasa, Szymon M.;
- Ungethüm, Ute;
- Lund, Per;
- Knösel, Thomas;
- Kemmner, Wolfgang;
- Morkel, Markus;
- Fritzmann, Johannes;
- Schlag, Peter M.;
- Birchmeier, Walter;
- Krueger, Tammo;
- Sperling, Silke;
- Sers, Christine;
- Royer, Hans-Dieter
Publication type:
Article
Robust detection of clinically relevant features in single-cell RNA profiles of patient-matched fresh and formalin-fixed paraffin-embedded (FFPE) lung cancer tissue.
Published in:
Cellular Oncology (2211-3428), 2024, v. 47, n. 4, p. 1221, doi. 10.1007/s13402-024-00922-0
By:
- Trinks, Alexandra;
- Milek, Miha;
- Beule, Dieter;
- Kluge, Julie;
- Florian, Stefan;
- Sers, Christine;
- Horst, David;
- Morkel, Markus;
- Bischoff, Philip
Publication type:
Article
MEDIPS: genome-wide differential coverage analysis of sequencing data derived from DNA enrichment experiments.
Published in:
Bioinformatics, 2014, v. 30, n. 2, p. 284, doi. 10.1093/bioinformatics/btt650
By:
- Lienhard, Matthias;
- Grimm, Christina;
- Morkel, Markus;
- Herwig, Ralf;
- Chavez, Lukas
Publication type:
Article

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