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- Title
Impact of a COVID-19 Outbreak in an Elderly Care Home after Primary Vaccination.
- Authors
Mauriz, Elba; Fernández-Vázquez, José P.; Díez-Flecha, Cristina; Reguero-Celada, Sofía; Fernández-Villa, Tania; Fernández-Somoano, Ana; Caylà, Joan A.; Lozano-García, Jesús A.; Vázquez-Casares, Ana M.; Martín-Sánchez, Vicente
- Abstract
Elderly care home residents are particularly vulnerable to COVID-19 due to immune-senescence, pre-existing medical conditions, and the risk of transmission from staff and visitors. This study aimed to describe the outcomes of a COVID-19 outbreak in a long-term care facility for elderly persons following the initial vaccination. A single-center, retrospective, observational design was used to analyze the variables associated with hospitalization and death rate by logistic regression. Adjusted odds ratios (aOR) and their 95% confidence intervals (CI) were calculated. Sixty-eight residents received the first dose of the COVID-19 vaccine. Despite being negative six days after vaccination, the performance of a second test 4 days later revealed 51 positives (75.0%) among residents and 18 among workers (56.3%). A total of 65 of the 68 residents (95.58%) had positive results with symptoms, whereas 34.9% required hospitalization, and 25.8% died. The best-fitting model to explain the distribution of cases reflects three points at the time of infection.. The time from vaccination to symptom onset explains the hospitalization and mortality rates since a day elapsed halves the risk of hospitalization (aOR = 0.57; CI = 0.38−0.75) and the risk of death by a quarter (aOR = 0.74; CI = 0.63−0.88). Nursing homes present an elevated risk of transmission and severity of SARS-CoV-2 infection. Although vaccination reduces the risk of hospitalization and death, extreme prevention and control measures are essential in these institutions despite the high vaccination coverage.
- Subjects
COVID-19 pandemic; ELDER care; LONG-term care facilities; OLDER people; VACCINATION
- Publication
Vaccines, 2023, Vol 11, Issue 8, p1382
- ISSN
2076-393X
- Publication type
Article
- DOI
10.3390/vaccines11081382