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- Title
Cost-utility analysis of cataract surgery in Japan: a probabilistic Markov modeling study.
- Abstract
Objective: To evaluate with the best available clinical data in Japan the cost-effectiveness of cataract surgery through the estimation of the incremental costs per quality-adjusted life years (QALYs) gained. Methods: A Markov model with a probabilistic cohort analysis was constructed to calculate the incremental costs per QALY gained by cataract surgery in Japan. A 1-year cycle length and a 20-year horizon were applied. Best available evidence in Japan supplied the model with data on the course of cataract surgery. Uncertainty was explored using univariate and probabilistic sensitivity analysis. Results: In base case analysis, cataract surgery was associated with incremental costs of Japanese yen (¥) 551,513 (US$ 6,920) and incremental effectiveness of 3.38 QALYs per one cataract patient. The incremental cost effectiveness ratio (ICER) was ¥ 163,331 (US$ 2,049) per QALY. In Monte Carlo simulation, the average patient with cataract surgery accrued 4.65 [95 % confidence interval (CI): 2.75-5.69] more QALYs than patients without surgery, giving an ICER of ¥ 118,460 (95 % CI: 73,516-207,926) (US$ 1,486) per QALY. Conclusions: Cataract surgery in Japan is highly cost-effective even when allowing for the uncertainty of the known variability that exists in estimates of the costs, utilities, and postoperative complication rate.
- Subjects
JAPAN; CATARACT surgery complications; CRYSTALLINE lens diseases; TREATMENT of eye diseases; MARKOV processes; MONTE Carlo method
- Publication
Japanese Journal of Ophthalmology, 2013, Vol 57, Issue 4, p391
- ISSN
0021-5155
- Publication type
Article
- DOI
10.1007/s10384-013-0238-8