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A new biologically active molecular scaffold: crystal structure of 7‐(3‐hydroxyphenyl)‐4‐methyl‐2H‐[1,2,4]triazolo[3,2‐c][1,2,4]triazole and selective antiproliferative activity of three isomeric triazolo–triazoles
- Published in:
- Acta Crystallographica Section C: Structural Chemistry, 2019, v. 75, n. 10, p. 1398, doi. 10.1107/S2053229619012403
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- Publication type:
- Article
A biophysical characterization of the folded domains of KCTD12: insights into interaction with the GABA<sub>B2</sub> receptor.
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- Journal of Molecular Recognition, 2013, v. 26, n. 10, p. 488, doi. 10.1002/jmr.2291
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- Publication type:
- Article
Probing the DNA Reactivity and the Anticancer Properties of a Novel Tubercidin-Pt(II) Complex.
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- Pharmaceutics, 2020, v. 12, n. 7, p. 627, doi. 10.3390/pharmaceutics12070627
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- Publication type:
- Article
Synthesis, Antiproliferative Activity, and DNA Binding Studies of Nucleoamino Acid-Containing Pt(II) Complexes.
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- Pharmaceuticals (14248247), 2020, v. 13, n. 10, p. 284, doi. 10.3390/ph13100284
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- Publication type:
- Article
High-Resolution Conformational Analysis of RGDechi-Derived Peptides Based on a Combination of NMR Spectroscopy and MD Simulations.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 19, p. 11039, doi. 10.3390/ijms231911039
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- Publication type:
- Article
Exploring the Molecular Interactions of Symmetrical and Unsymmetrical Selenoglycosides with Human Galectin-1 and Galectin-3.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 15, p. 8273, doi. 10.3390/ijms23158273
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- Article
Design, Synthesis, and Anticancer Activity of a Selenium-Containing Galectin-3 and Galectin-9N Inhibitor.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 5, p. 2581, doi. 10.3390/ijms23052581
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- Article
More Is Always Better Than One: The N-Terminal Domain of the Spike Protein as Another Emerging Target for Hampering the SARS-CoV-2 Attachment to Host Cells.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 12, p. 6462, doi. 10.3390/ijms22126462
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- Article
Toward G-Quadruplex-Based Anticancer Agents: Biophysical and Biological Studies of Novel AS1411 Derivatives.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 20, p. 7781, doi. 10.3390/ijms21207781
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- Article
Targeting the <italic>BCL2</italic> Gene Promoter G‐Quadruplex with a New Class of Furopyridazinone‐Based Molecules.
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- ChemMedChem, 2018, v. 13, n. 5, p. 406, doi. 10.1002/cmdc.201700749
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- Article
Cullin 3 Recognition Is Not a Universal Property among KCTD Proteins.
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- PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0126808
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- Publication type:
- Article
Cullin3 - BTB Interface: A Novel Target for Stapled Peptides.
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- PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0121149
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- Publication type:
- Article
RGDechi-hCit: αvβ3 Selective Pro-Apoptotic Peptide as Potential Carrier for Drug Delivery into Melanoma Metastatic Cells.
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- PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0106441
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- Publication type:
- Article
γ sulphate PNA (PNA S): Highly Selective DNA Binding Molecule Showing Promising Antigene Activity.
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- PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0035774
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- Publication type:
- Article
Antineoplastic Ribonucleases Selectively Kill Thyroid Carcinoma Cells Via Caspase-Mediated Induction of Apoptosis.
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- Journal of Clinical Endocrinology & Metabolism, 2003, v. 88, n. 6, p. 2900, doi. 10.1210/jc.2002-020373
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- Publication type:
- Article
Synthesis of a novel Fmoc-protected nucleoaminoacid for the solid phase assembly of 4-piperidyl glycine/ l-arginine-containing nucleopeptides and preliminary RN A interaction studies.
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- Amino Acids, 2010, v. 39, n. 3, p. 795, doi. 10.1007/s00726-010-0532-4
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- Publication type:
- Article
Synthesis, spectroscopic studies and biological activity of a novel nucleopeptide with Moloney murine leukemia virus reverse transcriptase inhibitory activity.
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- Amino Acids, 2010, v. 38, n. 5, p. 1489, doi. 10.1007/s00726-009-0361-5
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- Publication type:
- Article
Conformational studies of RGDechi peptide by natural‐abundance NMR spectroscopy.
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- Journal of Peptide Science, 2019, v. 25, n. 5, p. N.PAG, doi. 10.1002/psc.3166
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- Publication type:
- Article
Design, synthesis and characterization of a peptide able to bind proteins of the KCTD family: implications for KCTD-cullin 3 recognition.
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- Journal of Peptide Science, 2011, v. 17, n. 5, p. 373, doi. 10.1002/psc.1366
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- Publication type:
- Article
gH625 is a viral derived peptide for effective delivery of intrinsically disordered proteins.
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- International Journal of Nanomedicine, 2013, v. 8, p. 2555, doi. 10.2147/IJN.S44186
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- Publication type:
- Article
Identification of Mortalin as the Main Interactor of Mycalin A, a Poly-Brominated C-15 Acetogenin Sponge Metabolite, by MS-Based Proteomics.
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- Marine Drugs, 2024, v. 22, n. 2, p. 52, doi. 10.3390/md22020052
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- Publication type:
- Article
Synthesis of Brominated Lactones Related to Mycalin A: Selective Antiproliferative Activity on Metastatic Melanoma Cells and Inhibition of the Cell Migration.
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- Marine Drugs, 2023, v. 21, n. 6, p. 349, doi. 10.3390/md21060349
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- Publication type:
- Article
Antiproliferative Activity of Mycalin A and Its Analogues on Human Skin Melanoma and Human Cervical Cancer Cells.
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- Marine Drugs, 2020, v. 18, n. 8, p. 402, doi. 10.3390/md18080402
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- Article
Molecular insights into the role of the polyalanine region in mediating PHOX2B aggregation.
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- FEBS Journal, 2019, v. 286, n. 13, p. 2505, doi. 10.1111/febs.14841
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- Publication type:
- Article
Phosphodiester Silybin Dimers Powerful Radical Scavengers: A Antiproliferative Activity on Different Cancer Cell Lines.
- Published in:
- Molecules, 2022, v. 27, n. 5, p. 1, doi. 10.3390/molecules27051702
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- Publication type:
- Article
Molecular basis of the scalp-ear-nipple syndrome unraveled by the characterization of disease-causing KCTD1 mutants.
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- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-46911-4
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- Publication type:
- Article
Regulating levels of the neuromodulator d-serine in human brain: structural insight into pLG72 and d-amino acid oxidase interaction.
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- FEBS Journal, 2016, v. 283, n. 18, p. 3353, doi. 10.1111/febs.13809
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- Article
A new cryptic cationic antimicrobial peptide from human apolipoprotein E with antibacterial activity and immunomodulatory effects on human cells.
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- FEBS Journal, 2016, v. 283, n. 11, p. 2115, doi. 10.1111/febs.13725
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- Publication type:
- Article
VEGFR Recognition Interface of a Proangiogenic VEGF‐Mimetic Peptide Determined In Vitro and in the Presence of Endothelial Cells by NMR Spectroscopy.
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- Chemistry - A European Journal, 2018, v. 24, n. 44, p. 11461, doi. 10.1002/chem.201802117
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- Article
Benzodifuran Derivatives as Potential Antiproliferative Agents: Possible Correlation between Their Bioactivity and Aggregation Properties.
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- ChemPlusChem, 2017, v. 82, n. 2, p. 251, doi. 10.1002/cplu.201600547
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- Publication type:
- Article
Insight into conformational modification of alpha-synuclein in the presence of neuronal whole cells and of their isolated membranes.
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- FEBS Letters, 2015, v. 589, n. 7, p. 798, doi. 10.1016/j.febslet.2015.02.012
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- Article
Selective Targeting of αvβ5 Integrin in HepG2 Cell Line by RGDechi15D Peptide.
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- Molecules, 2020, v. 25, n. 18, p. 4298, doi. 10.3390/molecules25184298
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- Article
Structural features for the mechanism of antitumor action of a dimeric human pancreatic ribonuclease variant.
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- Protein Science: A Publication of the Protein Society, 2009, v. 18, n. 1, p. 50, doi. 10.1002/pro.6
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- Article
Editorial: Special Issue "Galectins: Structure, Function and Therapeutic Inhibitors".
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- 2024
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- Publication type:
- Case Study
Biophysical and Structural Characterization of the Interaction between Human Galectin-3 and the Lipopolysaccharide from Pseudomonas aeruginosa.
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 5, p. 2895, doi. 10.3390/ijms25052895
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- Publication type:
- Article
A Combined NMR and Computational Approach to Determine the RGDechi-hCit-α<sub>v</sub>β<sub>3</sub> Integrin Recognition Mode in Isolated Cell Membranes.
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- Chemistry - A European Journal, 2016, v. 22, n. 2, p. 681, doi. 10.1002/chem.201503126
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- Publication type:
- Article
Functional Binding Surface of a β-Hairpin VEGF Receptor Targeting Peptide Determined by NMR Spectroscopy in Living Cells.
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- Chemistry - A European Journal, 2015, v. 21, n. 1, p. 91, doi. 10.1002/chem.201403335
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- Publication type:
- Article
Mapping Functional Interaction Sites of Human Prune C-Terminal Domain by NMR Spectroscopy in Human Cell Lysates.
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- Chemistry - A European Journal, 2013, v. 19, n. 37, p. 12217, doi. 10.1002/chem.201302168
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- Publication type:
- Article
A selective α<sub>v</sub>β<sub>5</sub> integrin antagonist hidden into the anophelin family protein cE5 from the malaria vector Anopheles gambiae.
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- Peptide Science, 2018, v. 110, n. 5, p. N.PAG, doi. 10.1002/pep2.24054
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- Publication type:
- Article
Deciphering RGDechi peptide‐α<sub>5</sub>β<sub>1</sub> integrin interaction mode in isolated cell membranes.
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- Peptide Science, 2018, v. 110, n. 5, p. N.PAG, doi. 10.1002/pep2.24065
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- Publication type:
- Article
Thermal and Chemical Stability of Two Homologous POZ/BTB Domains of KCTD Proteins Characterized by a Different Oligomeric Organization.
- Published in:
- BioMed Research International, 2013, v. 2013, p. 1, doi. 10.1155/2013/162674
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- Publication type:
- Article