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- Title
血清胆红素水平与绝经后骨质疏松症相关性的临床 分析.
- Authors
王冀苏
- Abstract
Objective To investigate the effect of serum total bilirubin in the pathogenesis of postmenopausal osteoporosis. Methods By dual energy X-ray bone density instrument examination,a total of 282 postmenopausal women were divided normal bone mass group ( n = 93) ,early postmenopausal osteoporosis group ( n = 61) ,middle postmenopausal osteoporosis group ( n = 58) ,and late postmenopausal osteoporosis group ( n = 70) . Serum total bilirubin and bone turnover markers were detected. The relationship between serum total bilirubin,bone mineral density,and bone metabolism was analyzed. Results Bone mineral density was negatively correlated with age,β-CTX,and PTH,but positively correlated with BMI,25( OH2 ) D3 ,and serum total bilirubin. Logistics regression analysis revealed that age,BMI,TBIL,PTH,and PINP were independently associated with the occurrence of osteoporosis,and ALP and β-CTX were not associated with postmenopausal osteoporosis. Conclusion The decrease of serum total bilirubin level is an independent risk factor of postmenopausal osteoporosis.
- Subjects
OSTEOPOROSIS in women; MENOPAUSE -- Risk factors; BILIRUBIN; BONE density; BONE metabolism; PREVENTION
- Publication
Chinese Journal of Osteoporosis, 2017, Vol 23, Issue 7, p926
- ISSN
1006-7108
- Publication type
Article
- DOI
10.3969/j.issn.1006-7108.2017.07.018