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- Title
Increase in newly diagnosed type 1 diabetes in youth during the COVID‐19 pandemic in the United States: A multi‐center analysis.
- Authors
Wolf, Risa M.; Noor, Nudrat; Izquierdo, Roberto; Jett, Destiny; Rewers, Amanda; Majidi, Shideh; Sheanon, Nicole; Breidbart, Emily; Demeterco‐Berggren, Carla; Lee, Joyce M.; Kamboj, Manmohan K.; Ebekozien, Osagie
- Abstract
Background: An increase in newly diagnosed type 1 diabetes (T1D) has been posited during the COVID‐19 pandemic, but data are conflicting. We aimed to determine trends in newly diagnosed T1D and severity of presentation at diagnosis for pediatric and adolescent patients during COVID‐19 (2020) as compared to the previous year (2019) in a multi‐center analysis across the United States. Methods: This retrospective study from seven centers in the T1D Exchange Quality Improvement Collaborative (T1DX‐QI) included data on new onset T1D diagnosis and proportion in DKA at diagnosis from January 1 to December 31, 2020, compared to the prior year. Chi‐square tests were used to compare differences in patient characteristics during the pandemic period compared to the prior year. Results: Across seven sites, there were 1399 newly diagnosed T1D patients in 2020, compared to 1277 in 2019 (p = 0.007). A greater proportion of newly diagnosed patients presented in DKA in 2020 compared to 2019 (599/1399(42.8%) vs. 493/1277(38.6%), p = 0.02), with a higher proportion presenting with severe DKA (p = 0.01) as characterized by a pH <7.1 and/or bicarbonate of <5 mmol/L. Monthly data trends demonstrated a higher number of new T1D diagnoses over the spring and summer months (March to September) of 2020 compared to 2019 (p < 0.001). Conclusions: We found an increase in newly diagnosed T1D and a greater proportion presenting in DKA at diagnosis during the COVID‐19 pandemic compared to the prior year. Future longitudinal studies are needed to confirm these findings with population level data and determine the long‐term impact of COVID‐19 on diabetes trends.
- Subjects
UNITED States; RESEARCH; INDEPENDENT variables; TYPE 1 diabetes; RETROSPECTIVE studies; HEALTH outcome assessment; SEVERITY of illness index; COMPARATIVE studies; CHI-squared test; DESCRIPTIVE statistics; DATA analysis software; COVID-19 pandemic; DIABETIC acidosis; ADOLESCENCE
- Publication
Pediatric Diabetes, 2022, Vol 23, Issue 4, p433
- ISSN
1399-543X
- Publication type
Article
- DOI
10.1111/pedi.13328