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- Title
SYNTHESIS AND EVALUATION OF COMPOSITE SCAFFOLDS BASED ON PVDF FIBRES AND MINERAL POWDERS FOR MEDICAL APPLICATIONS.
- Authors
ALECU, ANDRADA-ELENA; GÎRJOABĂ, STEFANIA-ANDREEA; BEREGOI, MIHAELA; BACALUM, MIHAELA; RAILEANU, MINA; JINGA, SORIN-ION; BUSUIOC, CRISTINA
- Abstract
In this work, polyvinylidene fluoride (PVDF) fibres loaded with mineral powders, such as titanium dioxide (TiO2), barium titanate (BaTiO3), and calcium magnesium silicate (CaxMgSi2Oy), were prepared by electrospinning polymeric suspensions containing 20 wt.% PVDF and 3 wt.% powder. The piezoelectric polymer was combined with powders having antibacterial, piezoelectric, or bioactive properties, respectively, in the desire to obtain multifunctional materials compatible with the requirements of the medical field. All powders were characterized in terms of morphology and crystalline structure, which confirmed the nanometric character of TiO2 samples and micrometric one for the other two, as well as the lower crystallite size for TiO2 specimens as against BaTiO3 and CaxMgSi2Oy. The final fibrous scaffolds were homogeneous, composed of individual fibres with a diameter below 1 µm and decorated with aggregates of inorganic particles, placed either inside the fibres or attached to their surface. The biological evaluation demonstrated the superiority of the composites towards the plain polymer in terms of cell viability.
- Subjects
DIOPSIDE; MAGNESIUM silicates; FIBERS; BARIUM titanate; POWDERS; POLYVINYLIDENE fluoride; MINERALS
- Publication
Romanian Journal of Materials / Revista Romana de Materiale, 2023, Vol 53, Issue 3, p212
- ISSN
1583-3186
- Publication type
Article