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- Title
Astroviruses in Rabbits.
- Authors
Martella, Vito; Moschidou, Paschalina; Pinto, Pierfrancesco; Catella, Cristiana; Desario, Constantina; Larocca, Vittorio; Circella, Elena; Bànyai, Krisztian; Lavazza, Antonio; Magistrali, Chiara; Decaro, Nicola; Buonavoglia, Canio
- Abstract
By screening rabbits with enterocolitis or enteritis complex and asymptomatic rabbits, we identified a novel astrovirus. The virus was distantly related (19.3%-23.7% aa identity) in the capsid precursor to other mammalian astroviruses within the Mamastrovirus genus. By using real-time reverse transcription PCR, with specific primers and probes and targeting a conserved stretch in open reading frame 1b, we found rabbit astrovirus in 10 (43%) of 23 samples from animals with enteric disease and in 25 (18%) of 139 samples from asymptomatic animals in Italy during 2005-2008. The mean and median titers in the positive animals were 102x and 103x greater, respectively, in the symptomatic animals than in the asymptomatic animals. These findings support the idea that rabbit astroviruses should be included in the diagnostic algorithm of rabbit enteric disease and animal experiments to increase information obtained about their epidemiology and potential pathogenic role.
- Subjects
ASTROVIRUSES; RABBIT diseases; ENTEROCOLITIS; POLYMERASE chain reaction; INTESTINAL diseases; COMMUNICABLE diseases
- Publication
Emerging Infectious Diseases, 2011, Vol 17, Issue 12, p2287
- ISSN
1080-6040
- Publication type
Article
- DOI
10.3201/eid1712.110967