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- Title
Genetic association studies of the progression from hyperuricaemia to gout.
- Authors
Sumpter, Nicholas A; Takei, Riku; Leask, Megan P; Reynolds, Richard J; Merriman, Tony R
- Abstract
In the article, the authors present their study which analyzed the genetic association of the progression to gout from hyperuricaemia. Other topics include the role of the loci like SLC2A9 and ABCG2 in urate control, the use of age-adjusted sex-stratificed logistic regression models in the study, and the association of the weighted polygenic risk score (PRS) with gout, particularly in men.
- Subjects
UNITED Kingdom; HYPERURICEMIA; DISEASE progression; CONFIDENCE intervals; RISK assessment; URIC acid; ODDS ratio; LOGISTIC regression analysis; GOUT
- Publication
Rheumatology, 2022, Vol 61, Issue 6, pe139
- ISSN
1462-0324
- Publication type
Article
- DOI
10.1093/rheumatology/keac011