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- Title
Method for determining the number of aldehydes in dextran polyaldehyde using 2,4-dinitrophenylhydrazine.
- Authors
Medvedev, V.; Troitsky, A.; Bystrova, T.; Shkurupiy, V.
- Abstract
A method for determining the number of aldehydes in dextran polyaldehyde (DPA) was proposed. The method was based on the production of the DPAconjugate with 2,4-dinitrophenylhydrazine, reaction of which with base formed a colored product. The developed method for quantitative determination of aldehydes was distinguished from others by its simplicity and high sensitivity. Results of physicochemical studies of DPA and their derivatives were presented in order to identify their structures and formation mechanism in the presence of KMnO.
- Subjects
ALDEHYDES; DEXTRAN; POLYALDEHYDES; PHENYLHYDRAZINE; CHEMICAL reactions; QUANTITATIVE chemical analysis; MOLECULAR structure
- Publication
Pharmaceutical Chemistry Journal, 2012, Vol 46, Issue 9, p573
- ISSN
0091-150X
- Publication type
Article
- DOI
10.1007/s11094-012-0849-2