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- Title
Essential Thrombocythemia Transformed to Acute Myelogenous Leukemia with t(3;17)(p24; q12), del(5)(q13q34) After Treatment with Carboquone and Hydroxyurea.
- Authors
Tabata, Masahiko; Imagawa, Shigehiko; Tarumoto, Takahisa; Ohmine, Ken; Hatake, Kiyohiko; Miura, Yasusada; Ozawa, Keiya
- Abstract
Reports on the transformation of essential thrombocythemia to acute myelogenous leukemia after treatment with carboquone and hydroxyurea. Clinical manifestations; Severity of the disease; Agents that inhibit DNA synthesis and repair; Association between p53 gene mutation on chromosome 17 and chromosome 21 abberation.
- Subjects
THROMBOCYTOSIS; ACUTE myeloid leukemia; CHROMOSOME abnormalities
- Publication
Japanese Journal of Clinical Oncology, 2000, Vol 30, Issue 7, p310
- ISSN
0368-2811
- Publication type
Article
- DOI
10.1093/jjco/hyd084