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- Title
Moxibustion for Patients with Primary Dysmenorrhea at Different Intervention Time Points: A Randomized Controlled Trial.
- Authors
Liu, Li-ying; Li, Xiao-ji; Wei, Wei; Guo, Xiao-li; Zhu, Li-hua; Gao, Fei-fei; Liang, Fan-rong; Yu, Si-yi; Yang, Jie
- Abstract
Purpose: To investigate the effectiveness of moxibustion at different times of the menstrual cycle for patients with primary dysmenorrhea (PD). Patients and Methods: Participants were 208 patients allocated to three controlled groups: one pre-menstrual treatment group (Group A), one menstrual-onset treatment group (Group B), and one waiting-list group (Group C). Groups A and B received the same intervention of moxibustion on points SP6 and RN4 but at different times. Group C, the waiting-list group, received no treatment throughout the study. Cox Menstrual Symptom Scale (CMSS) score was the primary outcome. Secondary outcomes were visual analog scale (VAS) score of pain intensity, self-rating anxiety scale (SAS) score, and self-rating depression scale (SDS) score. CMSS and VAS scores were obtained at the baseline stage (three cycles), treatment stage (three cycles), and follow-up stage (three cycles), a total of seven evaluations. SAS and SDS scores were obtained on the day of group allocation and the first day of the follow-up stage, a total of two evaluations. Results: Baseline characteristics were comparable across the three groups. Pain duration (CMSS score) was significantly higher in Group C than in the other two groups at each evaluation (P< 0.001). There was also a significant difference in the improvement in pain duration between Group B and Group C (P< 0.001) throughout the trial. There were no significant changes in pain severity (CMSS score) after the 3-month treatment in Group A and Group B (P> 0.05). Secondary outcomes showed that pre-menstrual moxibustion (Group A) was as effective as menstrual-onset moxibustion (Group B) in relieving pain intensity (VAS score) and negative mood (SDS and SAS scores). Conclusion: Moxibustion appears as an effective treatment for PD. Pre-menstrual application is more effective than menstrual-onset application. Trial Registration Chictr.org.cn Identifier: ChiCTR-TRC-14004627.
- Subjects
RANDOMIZED controlled trials; MOXIBUSTION; DYSMENORRHEA; MENSTRUAL cycle; VISUAL analog scale
- Publication
Journal of Pain Research, 2020, Vol 13, p2653
- ISSN
1178-7090
- Publication type
Article
- DOI
10.2147/JPR.S270698