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- Title
Corrected QT interval and QT dispersion in temporal lobe epilepsy.
- Authors
Nasef, Maram Samy; Gaber, Ahmed Abdelmonem; Abdelhamid, Yousry Aboelnaga; Bastawy, Islam; Abdelhady, Salem Taha; Wahid el din, Mona Mokhtar
- Abstract
Background: Cardiac arrhythmias are expected among patients with epilepsy due to the effect of anti-epileptic drugs. Temporal lobe epilepsy also causes autonomic seizures that may affect heart rhythm. Prolongation of the corrected QT interval and QT dispersion is a risk factor for cardiac arrhythmia. Objectives: We aimed to assess corrected QT interval and QT dispersion in patients with epilepsy and if there is a difference between patients with temporal epilepsy versus non-temporal epilepsy. Methods: This study was conducted on 100 patients (50 patients with temporal epilepsy and 50 patients with non-temporal epilepsy) and 50 age- and sex-matched healthy controls. They underwent a prolonged (6 to 24 h) 22 channel computerized electroencephalogram monitor with a 10–20 system. QT dispersion, QT interval, and corrected QT interval (using Bazett's formula) were calculated. Results: This study showed significantly higher QT dispersion and corrected QT interval in patients with epilepsy when compared to the age- and sex-matched control group (P < 0.001, P < 0.001). Also, the corrected QT interval and QT dispersion were significantly higher in temporal epilepsy patients when compared to the non-temporal group (P < 0.001, P < 0.001). Conclusion: Corrected QT interval and QT dispersion are higher in epileptic patients and more among temporal epilepsy patients in comparison to non-temporal epilepsy patients.
- Subjects
TEMPORAL lobe epilepsy; ARRHYTHMIA; PEOPLE with epilepsy; DISPERSION (Chemistry)
- Publication
Egyptian Journal of Neurology, Psychiatry & Neurosurgery, 2021, Vol 57, Issue 1, p1
- ISSN
1110-1083
- Publication type
Article
- DOI
10.1186/s41983-020-00257-1