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- Title
Noma disease (cancrum oris, orofacial gangrene) in an acute myeloid leukemia patient: a case report.
- Authors
Park, Jiho; Kim, Sanghun; Shin, Seung-Woo; Lyu, Chuhl Joo; Kim, Dongwook
- Abstract
<bold>Background: </bold>Noma is a rare disease that occurs mainly in malnourished patients in developing countries. Noma starts as facial swelling and gingival necrosis that eventually necrotizes underlying tissues including the jaw bone, leaving severe disfigurement. It is reported extremely rarely in patients with severe immunosuppression or blood dyscrasia.<bold>Case Presentation: </bold>The gingivitis that occurred in a 12-year-old Asian female patient with acute myeloid leukemia was getting increasingly worse. Although the proper treatment was done, the patient's condition did not improve, and eventually, a large full-thickness defect was left in the maxillofacial part.<bold>Conclusions: </bold>Early diagnosis and management is the only way to prevent the progression, which leads to facial disfigurement. We present a case of noma in a pediatric acute myeloid leukemia patient, in which oral function was restored through surgical intervention.
- Subjects
ACUTE myeloid leukemia; GANGRENE; WOMEN patients; RARE diseases; ACUTE myeloid leukemia diagnosis; ORAL disease diagnosis; ORAL diseases; FACE; MALNUTRITION; DISEASE complications
- Publication
Journal of Medical Case Reports, 2022, Vol 16, Issue 1, p1
- ISSN
1752-1947
- Publication type
journal article
- DOI
10.1186/s13256-022-03317-7