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- Title
Solitary epidermolytic acanthoma.
- Authors
Kazlouskaya, Viktoryia; Lambe, Jennifer; Elston, Dirk
- Abstract
Background Solitary epidermolytic acanthoma is thought to be an uncommon lesion. It can present as a solitary, localized or disseminated process that is unrelated to the genetic form of icthyosis. Methods A retrospective review of solitary epidermolytic acanthomas was performed at the Ackerman Academy of Dermatopathology, NY, over a 2 year period. The clinical and histopathological features of solitary epidermolytic acanthomas were described in 64 biopsies from 60 individuals. In situ hybridization for human papillomavirus ( HPV) was performed on all genital lesions. Results The incidence of epidermolytic acanthomas in our series was higher than previously reported (27.8/100,000). Genital location was the most common and the incidence of genital lesions was 8/100,000. In situ hybridization showed no evidence of genital HPV types within the lesions. The histological features of solitary epidermolytic acanthoma were re-evaluated. Conclusions Genital skin was the most common location for solitary epidermolytic acanthoma, but we found no evidence to suggest a role for genital HPV types. A strong male predominance was noted, and the lesions demonstrate a wide range of clinical and pathological findings.
- Subjects
NEW York (State); DIAGNOSIS of genitalia diseases; PAPILLOMAVIRUSES; DIAGNOSTIC use of in-situ hybridization; PATHOLOGICAL anatomy; CLINICAL pathology
- Publication
Journal of Cutaneous Pathology, 2013, Vol 40, Issue 8, p701
- ISSN
0303-6987
- Publication type
Article
- DOI
10.1111/cup.12165