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- Title
Editorial: Mesenchymal Stromal Cell Therapy for Regenerative Medicine.
- Authors
Capilla-González, Vivian; Herranz-Pérez, Vicente; Sarabia-Estrada, Rachel; Kadri, Nadir; Moll, Guido
- Abstract
Cellular and Molecular Mechanisms Underlying Therapeutic Effects of MSCs An in-depth understanding of the molecular mechanisms underlying MSCs' beneficial therapeutic effects in different clinical indications is essential to manufacture safe and effective therapies tailored to the individual patient need (Moll et al., [24]). Keywords: mesenchymal stromal/stem cell (MSC); clinical translation; immunomodulation; regeneration; modes of action (MoA) EN mesenchymal stromal/stem cell (MSC) clinical translation immunomodulation regeneration modes of action (MoA) 1 6 6 05/31/22 20220526 NES 220526 Introduction Mesenchymal stromal/stem cell (MSC) therapies are increasingly explored as novel regenerative and immunomodulatory approaches to treat or prevent diseases (Pittenger et al., [26]; Hmadcha et al., [15]; Moll et al., [24]; Ringdén et al., [27]). These reviews give an excellent overview on the treatment of skin disease with "cell products" (i.e., MSC) and "cell-conditioned" media (CCM), as well as "MSC-derived exosomes" in dermatology. Merimi et al. and Sagaradze et al. give a general introduction on MSC therapy in their review articles " I The therapeutic potential of MSCs for regenerative medicine: current knowledge and future understandings i " and " I MSCs as critical contributors in tissue regeneration i .".
- Subjects
MYOCARDIAL reperfusion; STROMAL cells; SCHWANN cells; BONE regeneration; REGENERATIVE medicine; CELLULAR therapy; MESENCHYMAL stem cells; CYTOLOGY
- Publication
Frontiers in Cellular Neuroscience, 2022, p1
- ISSN
1662-5102
- Publication type
Article
- DOI
10.3389/fncel.2022.932281