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- Title
Kodamaea ohmeri: A rare yeast causing invasive infections in immunocompromised patients.
- Authors
Singh, Parul; Srivastava, Smriti; Varma, Sharin; Sharad, Neha; Ningombam, Aparna; Peddapulla, Chandan; Malhotra, Rajesh; Mathur, Purva
- Abstract
Introduction: Kodamaea ohmeri is a rare, recognized pathogen that has previously been isolated from environmental sources. The patients commonly affected by this yeast include immunocompromised as well as immunocompetent patients having several associated risk factors. Methodology: We report three cases in which K. ohmeri was isolated from blood using Bact T/ALERT. Identification was carried out by MALDI-TOF MS (Vitek-MS, BioMérieux, Marcy-l'Etoile, France) in addition to color characteristics on chromogenic media. The patients had diminished immune response on account of a multitude of comorbidities. Results: K. ohmeri can be misidentified as Candida tropicalis, Candida albicans, or Candida hemolounii by conventional methods; correct and timely identification can be achieved by MALDI-TOF MS. Antifungal susceptibility breakpoints for K. ohmeri are currently not defined. An Echinocandin was added to the treatment regimen of all three of the cases. Conclusions: Identification of K. ohmeri using conventional methods is difficult and unusual yeasts should be carefully observed, especially upon prolonged incubation.
- Subjects
FRANCE; IMMUNOCOMPROMISED patients; CANDIDA tropicalis; YEAST; CANDIDA albicans; CANDIDA
- Publication
Journal of Infection in Developing Countries, 2024, Vol 18, Issue 4, p636
- ISSN
2036-6590
- Publication type
Case Study
- DOI
10.3855/jidc.18517