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- Title
A Primary Solitary Tumor of the Lesser Omentum With Immunohistochemical Features of Gastrointestinal Stromal Tumors.
- Authors
Takahashi, Tsuyoshi; Kuwao, Sadahito; Yanagihara, Masatomo; Kakita, Akira
- Abstract
We here present a primary solitary tumor of the lesser momentum that was found in a 71-yr-old woman. Differential diagnosis could not be made preoperatively; therefore, histopathological examination including immunohistochemical studies were performed to determine the nature of the tumor. The resected specimen, measuring 17 cm at the largest point, consisted of the outer solid part and the inner mulliloculated cysts. Microscopically, the tumor was characterized by interlacing bundles of elongated spindle cells, with the nuclei focally showing a palisading pattern. However, skeinoid fibers were not observed anywhere. One to three mitoses per 50 high power fields were observed. Immunohistochemically, the tumor was negative for S-100 protein and smooth muscle-specific actin, but stained positive for CD34. The microscopic features were consistent with those of potentially malignant gastrointestinal stromal tumors. Stromal tumors that represent the differentiation toward neither typical leiomyomas or schwannomas rarely occur in the lesser omentum with only one such instance having been reported to date. Due to this rarity, it is difficult to make the differential diagnosis preoperatively, even with existing imaging techniques, and predicting the clinical behavior of such omental tumors is also often difficult. Therefore, complete resection should he performed when such tumors are encountered in daily practice.
- Subjects
OMENTUM tumors; IMMUNOHISTOCHEMISTRY; GASTROINTESTINAL diseases; CD antigens; SMOOTH muscle tumors
- Publication
American Journal of Gastroenterology (Springer Nature), 1998, Vol 93, Issue 11, p2269
- ISSN
0002-9270
- Publication type
Article
- DOI
10.1111/j.1572-0241.1998.00632.x