We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Contact-Dependent Growth Inhibition in Bacteria: Do Not Get Too Close!
- Authors
Ikryannikova, Larisa N.; Kurbatov, Leonid K.; Gorokhovets, Neonila V.; Zamyatnin Jr., Andrey A.
- Abstract
Over millions of years of evolution, bacteria have developed complex strategies for intra-and interspecies interactions and competition for ecological niches and resources. Contact-dependent growth inhibition systems (CDI) are designed to realize a direct physical contact of one bacterial cell with other cells in proximity via receptor-mediated toxin delivery. These systems are found in many microorganisms including clinically important human pathogens. The main purpose of these systems is to provide competitive advantages for the growth of the population. In addition, non-competitive roles for CDI toxin delivery systems including interbacterial signal transduction and mediators of bacterial collaboration have been suggested. In this review, our goal was to systematize the recent findings on the structure, mechanisms, and purpose of CDI systems in bacterial populations and discuss the potential biological and evolutionary impact of CDI-mediated interbacterial competition and/or cooperation.
- Subjects
COMPETITION (Biology); PHYSICAL contact; ECOLOGICAL niche; BACTERIAL population; BACTERIAL cells
- Publication
International Journal of Molecular Sciences, 2020, Vol 21, Issue 21, p7990
- ISSN
1661-6596
- Publication type
Article
- DOI
10.3390/ijms21217990