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- Title
The Effects of Astragalus membranaceus Active Extracts on Autophagy-Related Diseases.
- Authors
Shan, Hao; Zheng, Xueping; Li, Min
- Abstract
Autophagy is an evolutionarily conserved 'self-eating' process that maintains cellular, tissue, and organismal homeostasis. New studies on autophagy, mediated by subsets of autophagy proteins, are emerging in many physiological and pathological processes. Astragalusmembranaceus (AM), also named Huangqi, is one of the fundamental herbs in traditional Chinese medicine and its extracts have been proved to possess many biological activities related to autophagy, including anti-oxidation, anti-inflammation, anticancer, anti-photoaging, and improvement of cardiomyocyte function. Evidence suggests that AM extracts can have therapeutic potential in autophagy dysregulation-associated diseases because of their biological positive effects. Here we will review the literature concerning the effects of AM extracts on autophagy dysregulation-associated diseases.
- Subjects
AUTOPHAGY; HOMEOSTASIS; CHINESE medicine; HEART cells; ANTINEOPLASTIC agents
- Publication
International Journal of Molecular Sciences, 2019, Vol 20, Issue 8, p1904
- ISSN
1661-6596
- Publication type
Article
- DOI
10.3390/ijms20081904