We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
When a DEAD-Box Protein Is the Key: A Novel Role for DDX5 in Lung Pericyte Dysfunction.
- Authors
Farkas, Laszlo; Rojas, Mauricio
- Abstract
The article explores the role of pericyte dysfunction in pulmonary hypertension (PH) associated with intrauterine growth restriction (IUGR). It identifies DDX5 as a key factor, regulated by miR-205, influencing pericyte behavior and suggesting potential therapeutic targets for IUGR-associated PH. Topics include epigenetic regulation in lung diseases, pericyte involvement in vascular remodeling, and potential biomarkers for predicting PH.
- Subjects
LUNGS; VASCULAR remodeling; PULMONARY circulation; WEIGHT in infancy; VERY low birth weight; LOW birth weight; FETAL growth retardation; GESTATIONAL age
- Publication
American Journal of Respiratory Cell & Molecular Biology, 2024, Vol 70, Issue 5, p336
- ISSN
1044-1549
- Publication type
Article
- DOI
10.1165/rcmb.2024-0031ED