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- Title
Mixing Analysis for a Fermentation Broth of the Fungus Beauveria bassiana under Different Hydrodynamic Conditions in a Bioreactor.
- Authors
Núñez-Ramírez, D. M.; Valencia-López, J. J.; Calderas, F.; Solís-Soto, A.; López-Miranda, J.; Medrano-Roldán, H.; Medina-Torres, L.
- Abstract
The performances of radial-axial flow (Rushton-Maxflo impellers) and axial-radial flow (Maxflo-Rushton impellers) mixers in the laminar-transitional flow regime were experimentally and numerically investigated with Newtonian and non-Newtonian fluids. The rheological properties for a fermentation broth consisting of the fungus Beauveria bassiana were studied under different hydrodynamic conditions in these systems. The bioreactor was a continuous stirred-tank reactor (CSTR), set at different stirring velocities. The rheology of the systems exhibited shear-thinning behavior which was modeled with the power law model. The experimental hydrodynamics and configuration modes were compared and simulated with a model fluid system and by numerical criteria (computational fluid dynamics). The R-M mode was found to be more efficient than the M-R rotating mode in terms of energy and homogenization time. The results will help in the optimization of scale-up production of these fungi.
- Publication
Chemical Engineering & Technology, 2012, Vol 35, Issue 11, p1954
- ISSN
0930-7516
- Publication type
Article
- DOI
10.1002/ceat.201200130