We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Down-regulation of interferon-γ parallels clinical response to selective leukocyte apheresis in patients with inflammatory bowel disease: a 12-month follow-up study.
- Authors
Muratov, V.; Lundahl, J.; Ulfgren, A. K.; Elvin, K.; Fehrman, I.; Ahlborg, N.; Öst, Å.; Hittel, N.; Saniabadi, A.; Löfberg, R.
- Abstract
The article focuses on a study which correlated the clinical response to leukocyte apheresis with the expression of key cytokines in mucosal tissue, in peripheral leukocytes and in plasma. Seven patients with Crohn's disease and three patients with ulcerative colitis in median age were recruited for the study. For 5 consecutive weeks, leukocyte apheresis was performed once a week. The leukocyte apheresis procedures were well tolerated by the patients and there were no adverse effects encountered.
- Subjects
HEMAPHERESIS; LEUCOCYTES; CYTOKINES; ULCERATIVE colitis; CROHN'S disease; BLOOD plasma
- Publication
International Journal of Colorectal Disease, 2006, Vol 21, Issue 6, p493
- ISSN
0179-1958
- Publication type
Article
- DOI
10.1007/s00384-005-0069-2