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- Title
The Prevalence of Developmental Enamel Defects in Israeli Children and Its Association with Perinatal Conditions: A Cross-Sectional Study.
- Authors
Berenstein Ajzman, Gisela; Dagon, Nurit; Iraqi, Rabea; Blumer, Sigalit; Fadela, Shada
- Abstract
Molar incisor hypomineralization (MIH) and deciduous molar hypomineralization (DMH) affect the first permanent molars and second primary molars, respectively, causing a greater dental treatment burden and worse oral health quality of life among affected children. We assessed the prevalence and risk factors of MIH and DMH among 1209 children aged 3–13 years who attended a university dental clinic in Israel in 2019–2020. Clinical examinations were conducted to assess the presence of DMH and MIH. Potential etiological factors of MIH and DMH, including demographics, the mother's perinatal health, and the child's medical history during the first three years of life, were retrieved using a questionnaire. To examine the associations between the demographic and clinical variables and the prevalence of MIH and DMH, continuous variables were tested using the Kruskal–Wallis test with Bonferroni corrections. Categorical variables were analyzed by chi-squared test. Multivariate logistic regression was conducted to evaluate which of the significant variables found in the univariate analysis could predict a diagnosis of both MIH and DMH. The prevalence of MIH and DMH was 10.3% and 6.0%, respectively. Age ≥ 5 years, taking medications during pregnancy and severe lesions were associated with a greater risk for a diagnosis of DMH + MIH. Multivariate logistic regression with adjustment for age showed that the severity of hypomineralization was positively and significantly associated with a diagnosis of MIH + DMH with an odds ratio of 4.18 (95% confidence interval 1.26–17.16), p = 0.03. MIH should be diagnosed and monitored in young children to prevent further deterioration. Moreover, a preventive and restorative program for MIH should be established.
- Subjects
ISRAEL; TOOTH demineralization; KRUSKAL-Wallis Test; MOTHERS; CONFIDENCE intervals; MOLARS; CROSS-sectional method; DEVELOPMENTAL defects of enamel; HEALTH status indicators; RISK assessment; PRENATAL exposure delayed effects; QUESTIONNAIRES; DESCRIPTIVE statistics; CHI-squared test; LOGISTIC regression analysis; ODDS ratio; DATA analysis software; PERINATAL period; DISEASE risk factors; CHILDREN
- Publication
Children, 2023, Vol 10, Issue 5, p903
- ISSN
2227-9067
- Publication type
Article
- DOI
10.3390/children10050903