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- Title
Effect of vitamin D levels on lipid, glucose, vitamin B<sub>12 </sub> and C-reactive protein in acute ischemic stroke.
- Authors
Kozaci, Nalan; Caliskan, Cafer; Avci, Mustafa; Caliskan, Gulsum; Uysal, Ilhan
- Abstract
Aim: Stroke ranks second among the causes of death world wideand related disability and death rates are high. Recent studies have shown that vitamin D defciency is higher in patients with ischemic stroke compared to other patients and vitamin D defciency has emerged as a new risk factor. The aims of the study are to investigate the relation between levels of vitamin D in patients diagnosed with acute ischemic stroke with levels of vitamin B12, glucose, HbA1c, blood urea nitrogen (BUN), creatinine, C-reactive protein (CRP) and lipids, and to determine the effect of vitamin D defciency on other factors that increase the risk of acute ischemic stroke. Materials and Methods: Two thousand seven hundred thirty-four patients diagnosed with acute ischemic stroke were included in the study. Results of laboratory tests for levels of vitamin D, vitamin B12 , HDL cholesterol, LDL cholesterol, VLDL cholesterol, triglycerides, glucose, HbA1c, BUN, creatinine and CRP were recorded. Results: As for correlation between vitamin D and other parameters, positive correlations between vitamin D and age, vitamin B12 , BUN and creatinine, and negative correlations between vitamin D and triglycerides, LDL cholesterol, VLDL cholesterol, glucose, HbA1c and CRP were identifed. Vitamin D and HDL cholesterol showed no correlation in normal HDL values, but there was positive correlation in patients with HDL cholesterol levels <40 mg/dL. Conclusion: Vitamin D levels in patients that suffered ischemic stroke were signifcantly correlated with lipid metabolism, glucose metabolism, inflammation, kidney function and vitamin B12 levels.
- Subjects
VITAMIN D deficiency; ISCHEMIC stroke; BLOOD urea nitrogen; LIPID metabolism; C-reactive protein
- Publication
Annals of Medical of Research, 2021, Vol 28, Issue 5, p879
- ISSN
2636-7688
- Publication type
Article
- DOI
10.5455/annalsmedres.2020.04.399