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- Title
Kanserden Korunmada Beslenme Tarzının Önemi: Moleküler Düzeyde Bir Bakış.
- Authors
ÇELEBİER, Mustafa; ERCAN, Ayşe; KÖSE, Yavuz Bülent
- Abstract
Characterized by uncontrolled and abnormal growth, cancer is a disease with high mortality and morbidity rates, seen in developed and underdeveloped countries. Chemotherapy, radiotherapy and surgery are methods used to treat different stages of the disease. Additionally, alternative complementary methods and small changes in lifestyle are used preventially to avoid the disease. In this context, considering the possible relationship between nutrition style and the risk of cancer formation, researches focusing on the importance of nutritional choices for cancer prevention has increased dramatically. The primary purpose of this review is to evaluate the nutrients frequently used worldwide by considering their active metabolites and to explain their impact on the molecular pathways. Multidisciplinary scientific researches has shown that these effects can only be explained by the integrating genomic, proteomic and metabolomic studies. Nowadays, the role of small molecules affecting human health is clarified by multi omic studies using advanced analytical methods, called foodomics. In this review, four large cuisines that constitute the nutritional habits of a great majority of the world population and their indispensable elements are presented. Mediterranean cuisine and its important elements olive oil, tomatoes, garlic, rosemary, sage; Indian cuisine and its important elements turmeric, sumac, cumin, ginger, saffron; Chinese cuisine and its important elements soybeans, rice, broccoli; Mexican cuisine and its important element chili pepper are investigated. The relevant active ingredients that effect metabolic pathways and help cancer prevention were screened. Also, a general assessment of cancer types observed based on regions was performed and was associated with the findings obtained from up-to-date scientific researches. This review study is intended to be a useful summary resource for clinicians, dieticians and pharmacists.
- Publication
Journal of Traditional Medical Complementary Therapies, 2021, Vol 4, Issue 1, p109
- ISSN
2630-6425
- Publication type
Article
- DOI
10.5336/jtracom.2020-76125