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- Title
TOXICOLOGICAL EFFECTS OF LEAD ON HUMAN HEALTH: A COMPREHENSIVE REVIEW.
- Authors
Kumar, D. Veera Nagendra; Mohan, M. Rama; Krishnaiah, C. Venkata; Prasad, G. L. N.; Sreedevi, B.; Naik, R. Manohar Srinivas
- Abstract
Lead (Pb) toxicity has garnered attention from environmental scientists because of its detrimental impact on plants, animals and humans. Lead toxicity ranks among the most perilous metal poisonings, with avenues of entry including lead-based paint, dust, water, soil, tableware, and folk remedies. Children are particularly susceptible to its effects. Lead instigates oxidative stress by impeding glutathione replenishment and can provoke hemolytic anemia through lipid peroxidationinduced disruption of cellular membranes. Furthermore, it perturbs neurotransmitter levels and induces severe health complications, some fatal, due to organ damage. The primary objective of this review is to synthesize information on lead toxicity detection, its sources, and its mechanisms, encompassing its various toxicological impacts on human health. Additionally, it underscores strategies for lead toxicity prevention and treatment.
- Subjects
LEAD; CELL membranes; HEMOLYTIC anemia; TRADITIONAL medicine; LEAD exposure; LEAD toxicology
- Publication
Journal of Experimental Zoology India, 2024, Vol 27, Issue 2, p1583
- ISSN
0972-0030
- Publication type
Article
- DOI
10.51470/jez.2024.27.2.1583