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- Title
The Application Value of 4D-ASL in Evaluating the Efficacy of Cerebral Ischemic Stroke.
- Authors
LIN Xiaoyi; WAN Pinghua; LEI Da; LI Weixiang; ZHANG Zongli
- Abstract
This article explores the application value of four-dimensional arterial spin labeling (4D-ASL) in evaluating the efficacy of cerebral ischemic stroke (CIS). Forty-eight patients with CIS who were hospitalized in Chenjiaqiao Hospital from August 2021 to January 2023 within 7 days after the onset of the disease were selected to receive three-dimensional arterial spin labeling (3D-ASL), 4D-ASL magnetic resonance angiography (MRA) and functional independence measure (FIM) scores before and after treatment, respectively. The cerebral blood flow (CBF) in the infarct core area and contralateral mirror area were recorded, and the relationship between the CBF values before and after treatment was analyzed. The collateral circulation was judged according to the dotted or banded high signal around the infarct area of 3D-ASL image, and the correlation between relative CBF (rCBF) and FIM with and without collateral circulation was analyzed. The morphology of cerebral vessels was observed by 4D-ASL MRA. The results showed that the CBF values in the core area of the infarction before and after treatment were lower than those in the contralateral mirror area, and the CBF values before treatment were lower than those after treatment, with a statistically significant difference (P<0.05). The rCBF and FIM scores before and after treatment were lower than those after treatment. The rCBF and FIM scores before and after treatment were positively correlated, and the difference was statistically significant (P<0.05). Around the core infarction area, rCBF with collateral circulation was higher than that without collateral circulation (P< 0.05). 4D-ASL MRA showed collateral vessels in 12 cases, and the coincidence rate with 3D-ASL was 75%. 4D-ASL technology can effectively evaluate CBF and collateral circulation, dynamically display the morphology of cerebral vessels, and achieve the effect of digital subtraction angiography. 4D-ASL has certain predictive value in the evaluation of CIS efficacy.
- Subjects
ISCHEMIC stroke; MAGNETIC resonance angiography; DIGITAL subtraction angiography; COLLATERAL circulation; FUNCTIONAL independence measure; DRUG labeling
- Publication
Imaging Science & Photochemistry, 2023, Vol 41, Issue 5, p277
- ISSN
1674-0475
- Publication type
Article
- DOI
10.7517/issn.1674-0475.230707