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- Title
Systemic or Endoventricular Thrombolysis to Treat HeartWare Left Ventricle Assist Device Thrombosis: A Clinical Dilemma.
- Authors
Raffa, Giuseppe M.; D'Ancona, Giuseppe; Sciacca, Sergio; Pietrosi, Astrid; Hernandez Baravoglia, Cesar M.; Turrisi, Marco; Romano, Giuseppe; Armaro, Alessandro; Stringi, Vincenzo; Clemenza, Francesco; Pilato, Michele
- Abstract
Endoventricular thrombolytic procedure ( ETP) has been used to treat continuous-flow left ventricle assist device ( CF- LVAD) thrombosis. The study aims to investigate the occurrence of complications after ETP. Data were retrospectively reviewed and analyzed in a series of patients who underwent CF- LVAD followed by ETP. Since November 2010, 20 patients underwent HeartWare CF-L VAD implantation at our institute. Four patients (20%) developed pump thrombosis and underwent a total of nine ETPs with tissue plasminogen activator infused into the left ventricle. The mean age was 60.2 ± 9 years. ETP was performed via either the femoral ( n = 6) or radial artery ( n = 3). Five ETPs (55.5%) were complicated by left and right radial artery occlusion, two by groin hematomas, and one by femoral artery false aneurysm. ETP carries a strong risk of vascular access complications that, in CF- LVAD patients, may add to the already complex clinical profile and economic burden; thus, a less invasive treatment is advisable whenever required.
- Subjects
THROMBOLYTIC therapy; THROMBOSIS; HEART assist devices; LEFT heart ventricle; PLASMINOGEN activators
- Publication
Artificial Organs, 2015, Vol 39, Issue 6, p526
- ISSN
0160-564X
- Publication type
Article
- DOI
10.1111/aor.12423