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- Title
Synthesis, Characterization and Antioxidant Property of Quercetin-Tb(III) Complex.
- Authors
Nazhad Dolatabadi, Jafar Ezzati; Mokhtarzadeh, Ahad; Ghareghoran, Seyed Morteza; Dehghan, Gholamreza
- Abstract
Purpose: Nearly all of flavonoids are good metal chelators and can chelate many metal ions to form different complexes. This article describes a synthesis of Quercetin-Tb(III) in methanol, characterized by using elemental analysis, UV-visible and evaluation of its antioxidant properties. Methods: The formation of complexes is realized from the UV-visible spectra which shows that the successive formation of Quercetin-Tb(III) occurs. To find out the antioxidant activity variation and the role of Tb(III) ion on the antioxidant activity of the complexes different radical scavenging methods such as: 1,1-diphenyl-2-picrylhydrazyl (DPPH), ferric reducing antioxidant power (FRAP) and 2,2'-azinobis 3- ethylbenzothiazoline-6-sulphonic acid (ABTS) were used. Results: The results from DPPH, ABTS and FRAP methods showed that Quercetin and Quercetin-Tb(III) complex are capable of donating electron or hydrogen atom, and consequently could react with free radicals or terminate chain reactions in a time- and dose-dependent manner. Conclusion: This study showed that the chelation of metal ions by Quercetin decrease the redox potential of Quercetin-metal complex.
- Subjects
QUERCETIN; ANTIOXIDANTS; METAL ions; FLAVONOIDS; PHYTOCHEMICALS; ULTRAVIOLET-visible spectroscopy; OXIDATION-reduction reaction
- Publication
Advanced Pharmaceutical Bulletin, 2014, Vol 4, Issue 2, p101
- ISSN
2228-5881
- Publication type
Article
- DOI
10.5681/apb.2014.016