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Quantitative Relationships Between the Cytotoxicity of Flavonoids on the Human Breast Cancer Stem-Like Cells MCF7- SC and Their Structural Properties.
- Published in:
- Chemical Biology & Drug Design, 2015, v. 86, n. 4, p. 496, doi. 10.1111/cbdd.12512
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- Article
Plant-Derived Flavones as Inhibitors of Aurora B Kinase and Their Quantitative Structure-Activity Relationships.
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- Chemical Biology & Drug Design, 2015, v. 85, n. 5, p. 574, doi. 10.1111/cbdd.12445
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- Article
Suppression of Egr-1 transcription through targeting of the serum response factor by oncogenic H-Ras.
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- EMBO Journal, 2006, v. 25, n. 5, p. 1093, doi. 10.1038/sj.emboj.7600987
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- Article
β-Caryophyllene Ameliorates 2,4-Dinitrochlorobenzene-Induced Atopic Dermatitis through the Downregulation of Mitogen-Activated Protein Kinase/EGR1/TSLP Signaling Axis.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 23, p. 14861, doi. 10.3390/ijms232314861
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- Article
Saikosaponin A and Saikosaponin C Reduce TNF-α-Induced TSLP Expression through Inhibition of MAPK-Mediated EGR1 Expression in HaCaT Keratinocytes.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 9, p. 4857, doi. 10.3390/ijms23094857
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- Article
Chrysin Inhibits TNFα-Induced TSLP Expression through Downregulation of EGR1 Expression in Keratinocytes.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4350, doi. 10.3390/ijms22094350
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- Article
Chrysoeriol Prevents TNFα-Induced CYP19 Gene Expression via EGR-1 Downregulation in MCF7 Breast Cancer Cells.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 20, p. 7523, doi. 10.3390/ijms21207523
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- Article
Chrysin Inhibits NF-κB-Dependent CCL5 Transcription by Targeting IκB Kinase in the Atopic Dermatitis-Like Inflammatory Microenvironment.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 19, p. 7348, doi. 10.3390/ijms21197348
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- Article
A Novel Synthetic Compound (E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile Inhibits TNFα-Induced MMP9 Expression via EGR-1 Downregulation in MDA-MB-231 Human Breast Cancer Cells.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 14, p. 5080, doi. 10.3390/ijms21145080
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- Article
Inhibitory Effect of Synthetic Flavone Derivatives on Pan-Aurora Kinases: Induction of G2/M Cell-Cycle Arrest and Apoptosis in HCT116 Human Colon Cancer Cells.
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- International Journal of Molecular Sciences, 2018, v. 19, n. 12, p. 4086, doi. 10.3390/ijms19124086
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- Article
Inhibitory Effect of Alisma canaliculatum Ethanolic Extract on NF-κB-Dependent CXCR3 and CXCL10 Expression in TNFα-Exposed MDA-MB-231 Breast Cancer Cells.
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- International Journal of Molecular Sciences, 2018, v. 19, n. 9, p. 2607, doi. 10.3390/ijms19092607
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- Article
Downregulation of α-Melanocyte-Stimulating Hormone-Induced Activation of the Pax3-MITF-Tyrosinase Axis by Sorghum Ethanolic Extract in B16F10 Melanoma Cells.
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- International Journal of Molecular Sciences, 2018, v. 19, n. 6, p. 1640, doi. 10.3390/ijms19061640
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- Article
Structural Properties of Polyphenols Causing Cell Cycle Arrest at G1 Phase in HCT116 Human Colorectal Cancer Cell Lines.
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- International Journal of Molecular Sciences, 2013, v. 14, n. 8, p. 16970, doi. 10.3390/ijms140816970
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- Article
A Benzochalcone Derivative, (E)-1-(2-hydroxy-6-methoxyphenyl)-3-(naphthalen-2-yl)prop-2-en-1-one (DK-512), Inhibits Tumor Invasion through Inhibition of the TNFα-Induced NF-κB/MMP-9 Axis in MDA-MB-231 Breast Cancer Cells.
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- Journal of Chemistry, 2016, p. 1, doi. 10.1155/2016/4921717
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- Article
Effects of Combined Treatments of Lithium and Valproate on the Phosphorylation of ERK1/2 and Transcriptional Activity of ELK1 and C-FOS in PC12 Cells.
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- Korean Journal of Biological Psychiatry, 2013, v. 20, n. 4, p. 159
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- Article
Design, synthesis, and biological evaluation of polyphenols with 4,6-diphenylpyrimidin-2-amine derivatives for inhibition of Aurora kinase A.
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- DARU: Journal of Pharmaceutical Sciences, 2019, v. 27, p. 265, doi. 10.1007/s40199-019-00272-5
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- Article
<sup>1</sup>H and <sup>13</sup>C NMR spectral assignments for 24 novel naphthalenylphenylpyrazolines.
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- 2017
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- Publication type:
- Other
Synthesis and structure elucidation of polyphenols containing the N′-methyleneformohydrazide scaffold as aurora kinase inhibitors.
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- 2017
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- Publication type:
- Other
<sup>1</sup>H and <sup>13</sup>C NMR spectral assignments of flavone derivatives.
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- Magnetic Resonance in Chemistry, 2017, v. 55, n. 4, p. 359, doi. 10.1002/mrc.4535
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- Article
<sup>1</sup>H and <sup>13</sup>C NMR spectral assignments of novel flavonoids bearing benzothiazepine.
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- 2016
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- Publication type:
- Other
Up-regulation of TNF-alpha secretion by cigarette smoke is mediated by Egr-1 in HaCaT human keratinocytes.
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- Experimental Dermatology, 2010, v. 19, n. 8, p. e206, doi. 10.1111/j.1600-0625.2009.01050.x
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- Article
The UPR inducer DPP23 inhibits the metastatic potential of MDA-MB-231 human breast cancer cells by targeting the Akt-IKK-NF-κB-MMP-9 axis.
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- Scientific Reports, 2016, p. 34134, doi. 10.1038/srep34134
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- Publication type:
- Article
3-(5-Hydroxyphenyl)-5-Phenyl-2-Pyrazolines as Toll-Like Receptor 7 Agonists.
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- Journal of Chemistry, 2023, p. 1, doi. 10.1155/2023/2151669
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- Article
Synthesis, Crystal Structure, Hirshfeld Surface Analysis and Docking Studies of a Novel Flavone–Chalcone Hybrid Compound Demonstrating Anticancer Effects by Generating ROS through Glutathione Depletion.
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- Crystals (2073-4352), 2022, v. 12, n. 1, p. 108, doi. 10.3390/cryst12010108
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- Article
Single Crystal X-Ray Structure for the Disordered Two Independent Molecules of Novel Isoflavone: Synthesis, Hirshfeld Surface Analysis, Inhibition and Docking Studies on IKKβ of 3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-6,7-dimethoxy-4H-chromen-4-one.
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- Crystals (2073-4352), 2020, v. 10, n. 10, p. 911, doi. 10.3390/cryst10100911
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- Article
Synthesis, Single Crystal X-Ray Structure, Hirshfeld Surface Analysis, DFT Computations, Docking Studies on Aurora Kinases and an Anticancer Property of 3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-6-methoxy-4H-chromen-4-one.
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- Crystals (2073-4352), 2020, v. 10, n. 5, p. 413, doi. 10.3390/cryst10050413
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- Article
Ethanolic Extracts of Ageratum houstonium, Bupleurum falcatum, and Schisandra chinensis Inhibit Interleukin-4-Induced Expression of Itching Factors in HaCaT Keratinocytes.
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- Journal of Cosmetic Science, 2021, v. 72, n. 6, p. 580
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- Article
Regulation of Functional Phenotypes of Cord Blood-Derived Eosinophils by γ-Secretase Inhibitor.
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- American Journal of Respiratory Cell & Molecular Biology, 2007, v. 37, n. 5, p. 571, doi. 10.1165/rcmb.2006-0412OC
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- Publication type:
- Article
Regulation of pro-opiomelanocortin (POMC) gene transcription by interleukin-31 via early growth response 1 (EGR-1) in HaCaT keratinocytes.
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- Molecular Biology Reports, 2020, v. 47, n. 8, p. 5953, doi. 10.1007/s11033-020-05668-0
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- Article
Leptin is a direct transcriptional target of EGR1 in human breast cancer cells.
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- Molecular Biology Reports, 2019, v. 46, n. 1, p. 317, doi. 10.1007/s11033-018-4474-3
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- Article
Saikosaponin A Recovers Impaired Filaggrin Levels in Inflamed Skin by Downregulating the Expression of FRA1 and c-Jun.
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- Molecules, 2024, v. 29, n. 17, p. 4064, doi. 10.3390/molecules29174064
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- Article
Design, synthesis, and evaluation of 4-chromenone derivatives combined with N-acylhydrazone for aurora kinase A inhibitor.
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- Applied Biological Chemistry, 2021, v. 64, n. 1, p. 1, doi. 10.1186/s13765-021-00596-4
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- Article
Anticancer activities of cyclohexenone derivatives.
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- Applied Biological Chemistry, 2020, v. 63, n. 1, p. N.PAG, doi. 10.1186/s13765-020-00567-1
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- Article
A Synthetic Pan-Aurora Kinase Inhibitor, 5-Methoxy-2-(2-methoxynaphthalen-1-yl)-4H-chromen-4-one, Triggers Reactive Oxygen Species-Mediated Apoptosis in HCT116 Colon Cancer Cells.
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- Journal of Chemistry, 2020, p. 1, doi. 10.1155/2020/3025281
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- Publication type:
- Article
The antipsychotic agent chlorpromazine induces autophagic cell death by inhibiting the Akt/mTOR pathway in human U-87MG glioma cells.
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- Carcinogenesis, 2013, v. 34, n. 9, p. 2080, doi. 10.1093/carcin/bgt169
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- Article
Transcriptional regulation of the interleukin-11 gene by oncogenic Ras.
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- Carcinogenesis, 2012, v. 33, n. 12, p. 2467, doi. 10.1093/carcin/bgs297
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- Publication type:
- Article
Effect of 6,7-dimethoxy-2,2-dimethyl-2H-chromene (agerarin) on the recovery of filaggrin expression through targeting of Janus kinases in the inflammatory skin.
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- Journal of Food & Drug Analysis, 2020, v. 28, n. 3, p. 449, doi. 10.38212/2224-6614.1178
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- Article
The crystal structure of 2-(7-(2,3-dimethoxyphenyl)-[1,2,4]triazolo[1,5-a]-pyrimidin-5-yl)-3-methoxyphenol, C<sub>20</sub>H<sub>18</sub>N<sub>4</sub>O<sub>4</sub>.
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- Zeitschrift für Kristallographie / New Crystal Structures, 2023, v. 238, n. 2, p. 167, doi. 10.1515/ncrs-2022-0534
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- Publication type:
- Article
The crystal structure of ethyl 2′-hydroxy-4′,6′-dimethoxy-3-(4-methoxynaphthalen-1-yl)-5-oxo-2,3,4,5-tetrahydro-[1,1′-biphenyl]-4-carboxylate, C<sub>28</sub>H<sub>28</sub>O<sub>7</sub>.
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- Zeitschrift für Kristallographie / New Crystal Structures, 2023, v. 238, n. 1, p. 149, doi. 10.1515/ncrs-2022-0517
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- Article
The crystal structure of (Z)-2-(2,3-dimethoxybenzylidene)naphtho[1,2-b]furan-3(2H)-one, C<sub>21</sub>H<sub>16</sub>O<sub>4</sub>.
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- Zeitschrift für Kristallographie / New Crystal Structures, 2022, v. 237, n. 6, p. 1189, doi. 10.1515/ncrs-2022-0454
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- Article
The crystal structure of 2-(4-methoxynaphthalen-1-yl)-4H-chromen-4-one, C<sub>20</sub>H<sub>14</sub>O<sub>3</sub>.
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- Zeitschrift für Kristallographie / New Crystal Structures, 2022, v. 237, n. 6, p. 1171, doi. 10.1515/ncrs-2022-0446
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- Article
The crystal structure of ethyl 2-amino-4-(3,5-difluorophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate, C<sub>20</sub>H<sub>21</sub>F<sub>2</sub>NO<sub>4</sub>.
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- Zeitschrift für Kristallographie / New Crystal Structures, 2021, v. 236, n. 2, p. 307, doi. 10.1515/ncrs-2020-0566
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- Article
Negative regulatory role of overexpression of PLCγ1in the expression of early growth response 1 gene in rat 3Y1 fibroblasts.
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- FASEB Journal, 2002, v. 16, n. 12, p. 1504, doi. 10.1096/fj.02-0022com
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- Article
Effects of intravenous iron combined with low-dose recombinant human erythropoietin on transfusion requirements in iron-deficient patients undergoing bilateral total knee replacement arthroplasty (CME).
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- Transfusion, 2011, v. 51, n. 1, p. 118, doi. 10.1111/j.1537-2995.2010.02783.x
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- Article
Cell growth inhibitory effects of polyphenols with naphthalene skeleton against cisplatin-resistant ovarian cancer cells.
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- Applied Biological Chemistry, 2018, v. 61, n. 6, p. 697, doi. 10.1007/s13765-018-0403-3
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- Publication type:
- Article
Schisandra chinensis inhibiting TGFβ-induced activation of hepatic stellate cells.
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- Applied Biological Chemistry, 2018, v. 61, n. 6, p. 607, doi. 10.1007/s13765-018-0396-y
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- Publication type:
- Article
Relation between structures of naphthalenylchalcone derivatives and their cytotoxic effects on HCT116 human colon cancer cells.
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- Applied Biological Chemistry, 2018, v. 61, n. 3, p. 267, doi. 10.1007/s13765-018-0356-6
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- Publication type:
- Article
Clonogenic long-term survival assay of HCT 116 colorectal cancer cells after treatment with the synthesized diphenyl imidazoline derivatives.
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- Applied Biological Chemistry, 2018, v. 61, n. 3, p. 303, doi. 10.1007/s13765-018-0355-7
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- Publication type:
- Article
Inhibition of EGR-1-dependent MMP1 transcription by ethanol extract of Ageratum houstonianum in HaCaT keratinocytes.
- Published in:
- Molecular Biology Reports, 2021, v. 48, n. 1, p. 1, doi. 10.1007/s11033-020-06091-1
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- Publication type:
- Article
Aurora kinase A inhibitor TCS7010 demonstrates pro‑apoptotic effect through the unfolded protein response pathway in HCT116 colon cancer cells.
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- Oncology Letters, 2017, v. 14, n. 6, p. 6571, doi. 10.3892/ol.2017.7023
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- Article