We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Modeling human influenza infection in the laboratory.
- Authors
Radigan, Kathryn A.; Misharin, Alexander V.; Chi, Monica; Budinger, G. R. Scott
- Abstract
Influenza is the leading cause of death from an infectious cause. Because of its clinical importance, many investigators use animal models to understand the biologic mechanisms of influenza A virus replication, the immune response to the virus, and the efficacy of novel therapies. This review will focus on the biosafety, biosecurity, and ethical concerns that must be considered in pursuing influenza research, in addition to focusing on the two animal models - mice and ferrets - most frequently used by researchers as models of human influenza infection.
- Subjects
INFLUENZA research; ETIOLOGY of diseases; MEDICAL microbiology; INFECTION; INFLUENZA A virus; VIRUS diseases; RESPIRATORY infections
- Publication
Infection & Drug Resistance, 2015, Vol 8, p311
- ISSN
1178-6973
- Publication type
Article
- DOI
10.2147/IDR.S58551