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- Title
Normative values of retinal vessel oximetry in healthy children against adults.
- Authors
Waizel, Maria; Türksever, Cengiz; Todorova, Margarita G.
- Abstract
Background: Retinal oximetry (RO) has been established as a non‐invasive method to analyse oxygen saturation in retinal vessels. The aim of our study was to compare the RO parameters of healthy children to those in adults. Methods: A total of 200 eyes of 104 healthy subjects were examined: 20 eyes of children aged <10 years and 62 eyes of children aged 10–19 years were compared to the eyes of adult controls from five different age groups (20–29 years:n = 24; 30–39 years:n = 32; 40–49 years:n = 15; 50–59 years:n = 20, 60–80 years:n = 27; n indicates the number of analysed eyes). The oxygen saturation was estimated with the oxygen saturation measurement tool of the Retinal Vessel Analyser (RVA; IMEDOS Systems UG, Jena, Germany). The global oxygen saturations, within 1.0–1.5 optic disc diameters from the disc margin, in the peripapillary retinal arterioles (A‐SO2; %) and venules (V‐SO2; %) were estimated and their difference (A‐V SO2; %) was calculated. In addition, we evaluated the mean diameter in all four major retinal arterioles (D‐A; μm) and venules (D‐V; μm). The ratio between venular and arterial vessel diameter (D‐V/A; μm) was calculated thereafter. For statistical evaluation, anova‐based linear mixed‐effects models were calculated with spss®. Results: Based on our results, younger children (<10 years) present a statistically significant lower A‐SO2 and A‐V SO2 when compared to adult subgroups. The D‐A values revealed to be significantly lower in 10 + children when compared to the other groups, while the D‐V values did not show significant differences. Conclusion: These data indicate that the retinal oxygen metabolism changes throughout lifetime. Therefore, normative data for different age groups are mandatory.
- Subjects
JENA (Germany); GERMANY; RETINAL blood vessels; OPTIC disc; DISSOLVED oxygen in water; AGE groups; OXIMETRY
- Publication
Acta Ophthalmologica (1755375X), 2018, Vol 96, Issue 7, pe828
- ISSN
1755-375X
- Publication type
Article
- DOI
10.1111/aos.13726