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- Title
Malignant hyperthermia in Mazovia Province - are we adequately prepared?
- Authors
Cieniewicz, Agnieszka; Trzebicki, Janusz
- Abstract
Background: Malignant hyperthermia (MH) is a life-threatening syndrome caused by sudden skeletal muscle hypermetabolism in response to inhalation anaesthetics and depolarising relaxants. The estimated incidence of MH is between 1: 10,000 and 1: 250,000 anaesthetic procedures. In Poland the incidence of MH is unknown. Dantrolene is imported as a life-saving drug and temporally authorised for sale. The aim of the study is to assess the incidence of MH and access to dantrolene in the Mazovia Province. Methods: Anonymous questionnaires were sent to anaesthesia departments in the Mazovia Province after prior contact by phone and e-mail. The survey was approved by the local ethical review board. Results: Completed surveys were received from 60 respondents which represents 72% of anaesthesiology departments in Mazovia. In the last 5 years there have been 4 episodes of MH in the Mazovia Province. Three patients survived the MH crisis. In a centre that did not have access to dantrolene, the patient died. Dantrolene is found only in 11 (18.3%) anaesthesiology departments in Mazovia. Only 6 (10%) hospitals are able to administer dantrolene within 5 minutes of suspecting MH crisis, while 5 centres may receive it after a few days. Only 38% of units have an algorithm for dealing with MH crisis in the operating theatres. Conclusions: MH is rare, but if untreated, it can be fatal. Therefore prompt diagnosis and treatment are crucial to avoid fatal outcome. Every centre using inhalational anaesthetics and/or succinylcholine should have dantrolene. To ensure the safety of our patients, we must be better prepared.
- Subjects
POLAND; DANTROLENE; PERIOPERATIVE care; FEVER; HEALTH facilities; SURVEYS; QUESTIONNAIRES; PATIENT safety; ALGORITHMS
- Publication
Anaesthesiology Intensive Therapy / Anestezjologia, Intensywna Terapia, 2022, Vol 54, Issue 2, p99
- ISSN
1642-5758
- Publication type
Article
- DOI
10.5114/ait.2022.115348