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- Title
Phytochemical and Bioactivity Evaluation of Scrophularia amplexicaulis Benth.
- Authors
Pasdaran, Ardalan; Delazar, Abbas; Ayatollahi, Seyed Abdulmajid; Nahar, Lutfun; Sarker, Satyajit D.
- Abstract
Scrophularia amplexicaulis Benth. is an Iranian endemic species of the genus Scrophularia, which comprises ca. 200 medicinally important herbaceous flowering plants. Phytochemical investigation of the methanol extract of the aerial parts of this species afforded two iridoid glycosides, scropolioside D (1) and scrophuloside B4 (2), and two phenylalkanoid glycosides, salidroside (3) and verbascoside (4). Structures of these compounds were determined by comprehensive spectroscopic analyses. Free-radical-scavenging activity, potential antimalarial property, and contact toxicity as well as general toxicity of the extract and fractions were assessed.
- Subjects
PHYTOCHEMICALS; FIGWORTS; ENDEMIC plants; FREE radical scavengers; PLANT extracts; VERBASCOSIDE
- Publication
Records of Natural Products, 2016, Vol 10, Issue 4, p519
- ISSN
1307-6167
- Publication type
Article