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- Title
Capillaroscopy in 2016: new perspectives in systemic sclerosis.
- Authors
Pizzorni, C.; Sulli, A.; Smith, V.; Lladó, A.; Paolino, S.; Cutolo, M.; Ruaro, B.
- Abstract
Systemic sclerosis (SSc) is an autoimmune disorder of unknown etiology characterized by early impairment of the microvascular system. Nailfold microangiopathy and decreased peripheral blood perfusion are typical clinical aspects of SSc. The best method to evaluate vascular injury is nailfold videocapillaroscopy, which detects peripheral capillary morphology, and classifies and scores the abnormalities into different patterns of microangiopathy. Microangiopathy appears to be the best evaluable predictor of the disease development and has been observed to precede the other symptoms by many years. Peripheral blood perfusion is also impaired in SSc, and there are different methods to assess it: laser Doppler and laser speckle techniques, thermography and other emerging techniques.
- Subjects
CAPILLAROSCOPY; SYSTEMIC scleroderma; SPECKLE interference; THERMOGRAPHY; AUTOIMMUNE diseases
- Publication
Acta Reumatológica Portuguesa, 2016, Vol 41, Issue 1, p8
- ISSN
0303-464X
- Publication type
Article