We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Value of exercise radionuclide ventriculography and thallium-201 scintigraphy in evaluating successful coronary angioplasty: comparison with coronary flow reserve, translesional gradient and percent diameter stenosis.
- Authors
LEGRAND, V.; AUERON, F. M.; BATES, E. R.; O'NEILL, W. W.; HODGSON, J. MC. B.; MANCINI, G. B. J.; VOGEL, R. A.
- Abstract
Assessment of percutaneous transluminal coronary angioplasty (PTCA) by early radionuclide exercise test was evaluated for 11 arteries undergoing a successful procedure. Exercise thallium-201 (Tl-201) and radio-nuclide ventriculography (RNV) were performed within 3 days before and after PTCA and compared to % diameter stenosis, % translesional gradient and regional coronary flow reserve (CFR) determined by digital coronary angiography. Primary success of the procedure was gauged by reduction in % stenosis from 80 ± 12% to 31 ± 12% (residual stenosis < 50% in all cases) and reduction in % gradient < 25% in all cases). Before PTCA, Tl-201 and/or RNV were abnormal in all cases. After PTCA, radionuclide exercise tests improved but remained abnormal in 4 instances. No relationship was found between residual % gradient or stenosis and pathological Tl-201 or RNV following PTCA, but abnormal tests were observed among 4 out of the 5 vessels with the lowest CFR ( < 1.69). In one case CFR remained depressed despite good angiographic, hemodynamic and scintigraphic results, this patient had unstable angina before the procedure. Among patients with stable symptoms, CFR of arterial distributions with positive Tl-201 or RNV after PTCA was significantly lower than that with negative tests (1.58 ± 0.05 as compared to 1.90±0.25, P<0.02). Early radionuclide stress tests results thus reflect the physiologic improvement of coronary circulation. They may reflect the persistence of coronary flow abnormalities despite the relief of the epicardial stenosis.
- Publication
European Heart Journal, 1987, Vol 8, Issue 4, p329
- ISSN
0195-668X
- Publication type
Article
- DOI
10.1093/oxfordjournals.eurheartj.a062282