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- Title
Design and Synthesis of Chiral Oxathiozinone Scaffolds: Efficient Synthesis of Hindered Enantiopure Sulfinamides and Sulfinyl Ketimines.
- Authors
Han, Zhengxu S.; Herbage, Melissa A.; Mangunuru, Hari P. R.; Xu, Yibo; Zhang, Li; Reeves, Jonathan T.; Sieber, Joshua D.; Li, Zhibin; DeCroos, Philomen; Zhang, Yongda; Li, Guisheng; Li, Ning; Ma, Shengli; Grinberg, Nelu; Wang, Xiaojun; Goyal, Navneet; Krishnamurthy, Dhileep; Lu, Bruce; Song, Jinhua J.; Wang, Guijun
- Abstract
Is that SO? The title scaffolds have a highly active and properly differentiated SO bond for the efficient synthesis of enantiopure sulfinamides. The method is practical, green, and has the potential to provide an economical commercial process for the synthesis of bulky sulfinamides.
- Subjects
KETONE synthesis; SULFINYL compounds; ALKYL compounds; SULFINAMIDES; IMINES
- Publication
Angewandte Chemie International Edition, 2013, Vol 52, Issue 26, p6713
- ISSN
1433-7851
- Publication type
Article
- DOI
10.1002/anie.201301676