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- Title
Serological evidence of Mayaro virus infection in blood donors from São Carlos, São Paulo, Brazil.
- Authors
Romeiro, Marilia Farignoli; Fumagalli, Marcílio Jorge; Anjos, Ana Beatriz dos; Figueiredo, Luiz Tadeu Moraes
- Abstract
Background Human infections by Mayaro virus (MAYV) occur by insect bites upon exposure to rural or sylvatic areas. Information regarding MAYV transmission is limited due to a lack of commercial diagnostic assays and diagnostic confusion on account of similarities of clinical signs with other co-circulating arboviral diseases. Methods A serological survey of MAYV and Chikunguya virus (CHIKV) antibodies was performed by ELISA. Between 2017 and 2018, 5608 blood donor samples were tested. Results Specific IgM and IgG antibodies to MAYV were detected respectively in 36 and 11 samples, indicating a total seroprevalence of approximately 0.83%. Neutralization activity was observed in two IgG positive sera. Additionally, eight distinct samples had IgM antibodies to CHIKV alone. Conclusions Our data suggest previously unreported circulation of MAYV in São Carlos city, from southeastern Brazil.
- Subjects
SAO Paulo (Brazil); BRAZIL; VIRUS diseases; BLOOD donors; ARBOVIRUS diseases; SYMPTOMS; RURAL geography
- Publication
Transactions of the Royal Society of Tropical Medicine & Hygiene, 2020, Vol 114, Issue 9, p693
- ISSN
0035-9203
- Publication type
Article
- DOI
10.1093/trstmh/traa016