We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The Complete Amino Acid Sequence of Bovine Serum Amyloid Protein A (SAA) and of Subspecies of the Tissue-Deposited Amyloid Fibril Protein A.
- Authors
Rossevatn, K.; Andresen, P. K.; Sletten, K.; Husebekk, A.; Husby, G.; Nordstoga, K.; Johnson, K. H.; Westermark, G. T.; Westermark, P.
- Abstract
Bovine serum amyloid A (SAA) was isolated from the acute phase high density lipoprotein (HDL) fraction of a cow suffering from acute mastilis. The elucidated primary structure revealed a protein consisting of 112 amino acid residues. Compared with SAA proteins from other species, the bovine protein was shown to have an insertion of nine amino acid residues between positions 69 and 70. No microheterogeneity could be observed in the protein. Amyloid fibrils extracted from the kidneys were found to contain at least throe subspecies of protein AA, consisting of 68, 81 and about 110 amino acid residues. The amino acid sequences established for the protein AA subspecies revealed no microheterogeneity, and were Identical to that elucidated for protein SAA.
- Subjects
GLYCOPROTEINS; AMINO acids; ORGANIC acids; PROTEIN analysis; AMINO acid sequence; BLOOD plasma; AMYLOID beta-protein
- Publication
Scandinavian Journal of Immunology, 1992, Vol 35, Issue 2, p217
- ISSN
0300-9475
- Publication type
Article
- DOI
10.1111/j.1365-3083.1992.tb02853.x