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- Title
Medical Manuscript.
- Authors
Kim, Se Won; Hwang, In Cheol; Ahn, Hee Kyung; Kyung, Sun Young; Ahn, Hong Yup
- Abstract
The role of total serum testosterone in the prognosis of terminal cancer is unclear. We retrospectively investigated the total serum testosterone level in 69 male patients with terminal cancer in a palliative care unit. The association between the serum testosterone level and survival was assessed using Cox proportional hazard model. The median value of serum total testosterone was 44.5 ng/dL, far lower than previously reported in patients with advanced cancer. Multivariate analysis revealed thrombocytopenia (adjusted hazard ratio [aHR], 2.68), hypoalbuminemia (aHR, 2.02), azotemia (aHR, 2.67), and lower serum testosterone level (aHR, 2.03) were significantly negatively prognostic of survival. Lower serum testosterone level was an independent unfavorable prognostic factor for life expectancy in male patients with terminal cancer.
- Subjects
FISHER exact test; MANUSCRIPTS; MULTIVARIATE analysis; PALLIATIVE treatment; RESEARCH funding; SURVIVAL analysis (Biometry); TERMINALLY ill; TESTOSTERONE; RETROSPECTIVE studies; DESCRIPTIVE statistics
- Publication
American Journal of Hospice & Palliative Medicine, 2016, Vol 33, Issue 5, p483
- ISSN
1049-9091
- Publication type
Article
- DOI
10.1177/1049909115574492